Deep eutectic solvents: Recent advances in fabrication approaches and pharmaceutical applications

Y Liu, Y Wu, J Liu, W Wang, Q Yang, G Yang - International Journal of …, 2022 - Elsevier
Deep eutectic solvents (DESs) have received increasing attention in the past decade owing
to their distinguished properties including biocompatibility, tunability, thermal and chemical …

Deep eutectic systems: An overview of fundamental aspects, current understanding and drug delivery applications

S Chakraborty, JH Chormale, AK Bansal - International Journal of …, 2021 - Elsevier
The deep eutectic system (DES) is a relatively new concept in the field of drug delivery
science. DES is a class of eutectic mixtures comprised of two or more components, with a …

[HTML][HTML] Bioadhesive eutectogels supporting drug nanocrystals for long-acting delivery to mucosal tissues

MB Bianchi, C Zhang, E Catlin, G Sandri, M Calderón… - Materials Today Bio, 2022 - Elsevier
Eutectogels (Egels) are an emerging class of soft ionic materials outperforming traditional
temperature-intolerant hydrogels and costly ionogels. Due to their excellent elasticity, non …

Effect of graphene oxide and temperature on electrochemical polymerization of pyrrole and its stability performance in a novel eutectic solvent (choline chloride …

HK Ismail, IB Qader, HF Alesary, JH Kareem… - ACS …, 2022 - ACS Publications
Polypyrrole (Ppy)-modified graphene oxide (GO) electrodes were synthesized for the first
time in a choline chloride–phenol-based deep eutectic solvent at various temperatures via …

[HTML][HTML] Versatile applications of deep eutectic solvents in drug discovery and drug delivery systems: Perspectives and opportunities

M Hayyan - Asian Journal of Pharmaceutical Sciences, 2023 - ncbi.nlm.nih.gov
Recent years have seen notable progress in the use of deep eutectic solvents (DESs) in
pharmaceutical applications. This is ascribed to the high preparation flexibility of DES …

Deep eutectic systems as novel vehicles for assisting drug transdermal delivery

J Wang, M Li, L Duan, Y Lin, X Cui, Y Yang, C Wang - Pharmaceutics, 2022 - mdpi.com
In recent years, deep eutectic systems (DES) emerged as novel vehicles for facilitating the
transdermal delivery of various drugs, including polysaccharides, proteins, insulin, vaccine …

Current development of chemical penetration enhancers for transdermal insulin delivery

V Sugumar, M Hayyan, P Madhavan, WF Wong… - Biomedicines, 2023 - mdpi.com
The use of the transdermal delivery system has recently gained ample recognition due to the
ability to deliver drug molecules across the skin membrane, serving as an alternative to …

DES-igning the future of drug delivery: A journey from fundamentals to drug delivery applications

S Kapre, SS Palakurthi, A Jain, S Palakurthi - Journal of Molecular Liquids, 2024 - Elsevier
The pharmaceutical industry relies extensively on solvents for various purposes, including
synthesis, crystallization, purification, solubilization, and developing drug delivery systems …

Selective extraction of antioxidants by formation of a deep eutectic mixture through mechanical mixing

IB Qader, M Laguerre, A Lavaud, M Tenon… - ACS Sustainable …, 2023 - ACS Publications
Extraction of active compounds from natural materials is commonly used to produce a
diverse range of ingredients, nutrients, drugs, flavors, and fragrances. While solvent-based …

Electrochemical sensor based on polypyrrole/triiron tetraoxide (PPY/Fe3O4) nanocomposite deposited from a deep eutectic solvent for voltammetric determination of …

IB Qader, HK Ismail, HF Alesary, JH Kareem… - Journal of …, 2023 - Elsevier
This investigation reports the electrochemical preparation of a polypyrrole/triiron tetraoxide
(PPY/Fe 3 O 4) nanocomposite from deep eutectic solvents (DESs), and their application as …