Current status of antifungal susceptibility testing methods

S Arikan - Medical mycology, 2007 - academic.oup.com
Antifungal susceptibility testing is a very dynamic field of medical mycology. Standardization
of in vitro susceptibility tests by the Clinical and Laboratory Standards Institute (CLSI) and …

Combination therapy to treat fungal biofilm-based infections

J Tits, BPA Cammue, K Thevissen - International Journal of Molecular …, 2020 - mdpi.com
An increasing number of people is affected by fungal biofilm-based infections, which are
resistant to the majority of currently-used antifungal drugs. Such infections are often caused …

A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi

TF Dos Reis, PA De Castro, RW Bastos… - Nature …, 2023 - nature.com
Fungal infections cause more than 1.5 million deaths a year. Due to emerging antifungal
drug resistance, novel strategies are urgently needed to combat life-threatening fungal …

Defining fractional inhibitory concentration index cutoffs for additive interactions based on self-drug additive combinations, Monte Carlo simulation analysis, and in …

J Meletiadis, S Pournaras, E Roilides… - Antimicrobial agents …, 2010 - Am Soc Microbiol
The fractional inhibitory concentration (FIC) index range of 0.5 to 4 that is commonly used to
define additivity results in no interactions in most combination studies of antifungal agents …

Evaluation of the Antimicrobial and Antivirulent Potential of Essential Oils Isolated from Juniperus oxycedrus L. ssp. macrocarpa Aerial Parts

G Spengler, M Gajdács, MG Donadu, M Usai… - Microorganisms, 2022 - mdpi.com
As a consequence of the worsening situation with multidrug-resistant (MDR) pathogens and
a disparity in the commercialization of novel antimicrobial agents, scientists have been …

[HTML][HTML] Cerium oxide nanoparticles as potential antibiotic adjuvant. Effects of CeO2 nanoparticles on bacterial outer membrane permeability

P Bellio, C Luzi, A Mancini, S Cracchiolo… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Abstract Background Therapeutic options against Multi Drug Resistant (MDR) pathogens
are limited and the overall strategy would be the development of adjuvants able to enhance …

In vitro interactions between farnesol and fluconazole, amphotericin B or micafungin against Candida albicans biofilms

A Katragkou, M McCarthy, EL Alexander… - Journal of …, 2015 - academic.oup.com
Objectives Biofilm formation by Candida albicans poses an important therapeutic challenge
in human diseases. Typically, conventional antifungal agents encounter difficulty in treating …

Antifungal Activity and Mechanism of Action of the Co(III) Coordination Complexes With Diamine Chelate Ligands Against Reference and Clinical Strains of Candida …

K Turecka, A Chylewska, A Kawiak… - Frontiers in …, 2018 - frontiersin.org
Although many antifungal agents are available in clinical treatment, increasing resistance of
fungi, especially Candida species, to the available drugs requires the development of new …

In vitro and in vivo Effect of Exogenous Farnesol Exposure Against Candida auris

F Nagy, E Vitális, Á Jakab, AM Borman… - Frontiers in …, 2020 - frontiersin.org
The spreading of multidrug-resistant Candida auris is considered as an emerging global
health threat. The number of effective therapeutic regimens is strongly limited; therefore …

Enhanced activity of antifungal drugs using natural phenolics against yeast strains of Candida and Cryptococcus

NCG Faria, JH Kim, LAP Gonçalves… - Letters in applied …, 2011 - academic.oup.com
Aims: Determine whether certain, natural phenolic compounds enhance activity of
commercial antifungal drugs against yeast strains of Candida and Cryptococcus …