Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in
preclinical models and emerging evidence in humans have established the crucial roles of …

There is now overwhelming experimental and clinical evidence that atherosclerosis is a
chronic inflammatory disease. Lessons from genome-wide association studies, advanced in …

Observations on human and experimental atherosclerosis, biomarker studies, and now a
large-scale clinical trial support the operation of immune and inflammatory pathways in this …

Cardiovascular disease is the leading cause of death worldwide, both in the general
population and among patients with chronic kidney disease (CKD). In most cases, the …

Atherosclerosis is an arterial disease process characterized by the focal subendothelial
accumulation of apolipoprotein-B-containing lipoproteins, immune and vascular wall cells …

Atherosclerosis is a lipid-driven chronic inflammatory disease; however, whether it can be
classified as an autoimmune disease remains unclear. In this study, we applied single-cell T …

Atherosclerotic cardiovascular disease is a major cause of death among humans. Animal
models have shown that cholesterol and inflammation are causatively involved in the …

Many measures can control lipid risk factors for atherosclerosis. Yet, even with excellent
control of dyslipidemia, other sources of risk remain. Hence, we must look beyond lipids to …

Therapeutic vaccination offers great promise as an intervention for a diversity of infectious
and non‐infectious conditions. Given that most chronic health conditions are thought to have …

Circulating apolipoprotein B-containing lipoproteins, notably the low-density lipoproteins,
enter the inner layer of the arterial wall, the intima, where a fraction of them is retained and …