Ivermectin as a potential drug for treatment of COVID-19: an in-sync review with clinical and computational attributes
H Kaur, N Shekhar, S Sharma, P Sarma… - Pharmacological …, 2021 - Springer
Introduction COVID-19 cases are on surge; however, there is no efficient treatment or
vaccine that can be used for its management. Numerous clinical trials are being reviewed for …
vaccine that can be used for its management. Numerous clinical trials are being reviewed for …
The pharmacokinetics and metabolism of ivermectin in domestic animal species
The pharmacokinetic properties of drugs are closely related to their pharmacological
efficacy. The kinetics of ivermectin are characterised, in general terms, by a slow absorption …
efficacy. The kinetics of ivermectin are characterised, in general terms, by a slow absorption …
The approved dose of ivermectin alone is not the ideal dose for the treatment of COVID‐19
VD Schmith, J Zhou, LRL Lohmer - Clinical Pharmacology & …, 2020 - Wiley Online Library
Caly et al. 1 reported that ivermectin inhibited severe acute respiratory syndrome‐
coronavirus 2 (SARS‐CoV‐2) in vitro for up to 48 hours using ivermectin at 5 μM. The …
coronavirus 2 (SARS‐CoV‐2) in vitro for up to 48 hours using ivermectin at 5 μM. The …
Controlled randomized clinical trial on using Ivermectin with Doxycycline for treating COVID-19 patients in Baghdad, Iraq
HA Hashim, MF Maulood, AM Rasheed, DF Fatak… - MedRxiv, 2020 - medrxiv.org
Objectives COVID-19 patients suffer from the lack of curative therapy. Hence, there is an
urgent need to try repurposed old drugs on COVID-19. Methods Randomized controlled …
urgent need to try repurposed old drugs on COVID-19. Methods Randomized controlled …
Antiviral effect of high-dose ivermectin in adults with COVID-19: a proof-of-concept randomized trial
A Krolewiecki, A Lifschitz, M Moragas, M Travacio… - …, 2021 - thelancet.com
Background There are limited antiviral options for the treatment of patients with COVID-19.
Ivermectin (IVM), a macrocyclic lactone with a wide anti-parasitary spectrum, has shown …
Ivermectin (IVM), a macrocyclic lactone with a wide anti-parasitary spectrum, has shown …
Ivermectin as an adjunct treatment for hospitalized adult COVID-19 patients: a randomized multi-center clinical trial
MS Niaee, P Namdar, A Allami, L Zolghadr… - Asian Pacific Journal …, 2021 - journals.lww.com
Objective: To evaluate different doses of ivermectin in adult patients with mild COVID-19 and
to evaluate the effect of ivermectin on mortality and clinical consequences. Methods: A …
to evaluate the effect of ivermectin on mortality and clinical consequences. Methods: A …
[HTML][HTML] High-dose ivermectin for early treatment of COVID-19 (COVER study): a randomised, double-blind, multicentre, phase II, dose-finding, proof-of-concept …
D Buonfrate, F Chesini, D Martini… - International journal of …, 2022 - Elsevier
High concentrations of ivermectin demonstrated antiviral activity against SARS-CoV-2 in
vitro. The aim of this study was to assess the safety and efficacy of high-dose ivermectin in …
vitro. The aim of this study was to assess the safety and efficacy of high-dose ivermectin in …
Attenuation of clinical and immunological outcomes during SARS‐CoV‐2 infection by ivermectin
GD de Melo, F Lazarini, F Larrous, L Feige… - EMBO molecular …, 2021 - embopress.org
The devastating pandemic due to SARS‐CoV‐2 and the emergence of antigenic variants
that jeopardize the efficacy of current vaccines create an urgent need for a comprehensive …
that jeopardize the efficacy of current vaccines create an urgent need for a comprehensive …
Pharmacokinetic considerations on the repurposing of ivermectin for treatment of COVID‐19
R Peña‐Silva, SB Duffull, AC Steer… - British journal of …, 2020 - pmc.ncbi.nlm.nih.gov
Hundreds of researchers are working to develop a vaccine and are evaluating drugs to
mitigate the adverse health and economic consequences of COVID-19 (Coronavirus …
mitigate the adverse health and economic consequences of COVID-19 (Coronavirus …
Biodegradable polymers and their potential use in parenteral veterinary drug delivery systems
G Winzenburg, C Schmidt, S Fuchs, T Kissel - Advanced drug delivery …, 2004 - Elsevier
Biodegradable polymers have been extensively studied for numerous drug delivery systems
for human health purposes. The ever-increasing value of animals to human society allows …
for human health purposes. The ever-increasing value of animals to human society allows …