The WNT signaling pathway is a critical regulator of development and adult tissue
homeostasis and becomes dysregulated in many cancer types. Although hyperactivation of …

The Wnt signaling pathway is critically involved in both the development and homeostasis of
tissues via regulation of their endogenous stem cells. Aberrant Wnt signaling has been …

WNT–β-catenin signalling is involved in a multitude of developmental processes and the
maintenance of adult tissue homeostasis by regulating cell proliferation, differentiation …

Wnt signaling is crucial for embryonic development in all animal species studied to date. The
interaction between Wnt proteins and cell surface receptors can result in a variety of …

Wnt signaling transduces evolutionarily conserved pathways which play important roles in
initiating and regulating a diverse range of cellular activities, including cell proliferation …

Wnt proteins are now recognized as one of the major families of developmentally important
signaling molecules, with mutations in Wnt genes displaying remarkable phenotypes in the …

THE amiloride-sensitive epithelial sodium channel constitutes the rate-limiting step for
sodium reabsorption in epithelial cells that line the distal part of the renal tubule, the distal …

Receptors for Wingless and other signalling molecules of the Wnt gene family have yet to be
identified. We show here that cultured Drosophila cells transfected with a novel member of …

Wnt genes and components of Wnt signalling pathways have been implicated in a wide
spectrum of important biological phenomena, ranging from early organismal development to …

Summary The To//gene of Drosophila, a maternal effect gene that plays a central role in the
establishment of the embryonic dorsal-ventral pattern, has been cloned using P element …