The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

Melatonin production is highly conserved in nature through different species including
bacteria, unicellular eukaryotes, algae, plants invertebrates, and vertebrates (Hardeland et …

Interleukin-6 is an inflammatory cytokine with wide-ranging biological effects. It has been
widely demonstrated that neuroinflammation plays a critical role in the development of …

Major depressive disorder is the most common mental disorder with significant economic
burden and limited treatments. Acupuncture has emerged as a promising non …

Acupuncture reduces pain by activating specific areas called acupoints on the patient's
body. When these acupoints are fully activated, sensations of soreness, numbness, fullness …

An overview of the cannabinoid type 2 receptor system and it... : Current Opinion in
Anesthesiology An overview of the cannabinoid type 2 receptor system and its therapeutic …

Background The “classic” endocannabinoid (eCB) system includes the cannabinoid
receptors CB1 and CB2, the eCB ligands anandamide (AEA) and 2-arachidonoylglycerol (2 …

The endocannabinoid system (eCB) has been studied to identify the molecular structures
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …

Inflammatory pain is caused by peripheral tissue injury and inflammation. Inflammation
leads to peripheral sensitization, which may further cause central sensitization, resulting in …

Phytocannabinoids are naturally occurring compounds, the main source of which is
Cannabis sativa L. Through direct action or interaction with G protein-coupled receptors …