Biological relevance of RGD‐integrin subtype‐specific ligands in cancer

S Sani, M Messe, Q Fuchs, M Pierrevelcin… - …, 2021 - Wiley Online Library
Integrins are heterodimeric transmembrane proteins able to connect cells with the micro‐
environment. They represent a family of receptors involved in almost all the hallmarks of …

Fusobacterium Nucleatum Promotes the Development of Colorectal Cancer by Activating a Cytochrome P450/Epoxyoctadecenoic Acid Axis via TLR4/Keap1/NRF2 …

C Kong, X Yan, Y Zhu, H Zhu, Y Luo, P Liu… - Cancer Research, 2021 - AACR
Emerging research has revealed regulation of colorectal cancer metabolism by bacteria.
Fusobacterium nucleatum (Fn) plays a crucial role in the development of colorectal cancer …

[HTML][HTML] An inflammatory response-related gene signature can impact the immune status and predict the prognosis of hepatocellular carcinoma

Z Lin, Q Xu, D Miao, F Yu - Frontiers in oncology, 2021 - frontiersin.org
Background Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, which
makes the prognostic prediction challenging. As part of the active cross-talk between the …

Genes involved in the epithelial-mesenchymal transition in oral cancer: A systematic review

C Vallina, RM López-Pintor, J Gonzalez-Serrano… - Oral Oncology, 2021 - Elsevier
Objective Epithelial-mesenchymal transition (EMT) is considered the initial step in the
invasion-metastasis cascade. The aim of this systematic review was to study the signature of …

[HTML][HTML] ITGA5 is a prognostic biomarker and correlated with immune infiltration in gastrointestinal tumors

H Zhu, G Wang, H Zhu, A Xu - BMC cancer, 2021 - Springer
Abstract Background Integrin Subunit Alpha 5 (ITGA5), belongs to the integrin alpha chain
family, is vital for promoting cancer cell invasion, metastasis. However, the correlation …

[HTML][HTML] Evolution of mutational landscape and tumor immune-microenvironment in liver oligo-metastatic colorectal cancer

A Ottaiano, M Caraglia, A Di Mauro, G Botti… - Cancers, 2020 - mdpi.com
Simple Summary About 10% of colorectal cancer patients presents with oligo-metastatic
disease. The aim of our study was to assess genetic and immunologic dynamics underlying …

[HTML][HTML] Construction and verification of a fibroblast-related prognostic signature model for colon cancer

Z Zhao, W Li, LM Zhu, B Xu, Y Jiang, N Ma… - Frontiers in …, 2022 - frontiersin.org
Traditionally, cancer-associated fibroblasts (CAFs), an essential component of tumor
microenvironment, were exert a crucial part in colon cancer progression. In this study, single …

[HTML][HTML] Cancer immune exclusion: breaking the barricade for a successful immunotherapy

S Bruni, MF Mercogliano, FL Mauro… - Frontiers in …, 2023 - frontiersin.org
Immunotherapy has changed the course of cancer treatment. The initial steps were made
through tumor-specific antibodies that guided the setup of an antitumor immune response. A …

[HTML][HTML] The Expression Pattern of Adhesion G Protein-Coupled Receptor F5 Is Related to Cell Adhesion and Metastatic Pathways in Colorectal Cancer …

H Kang, J Fichna, K Matlawska-Wasowska, D Jacenik - Cells, 2022 - mdpi.com
Adhesion G protein-coupled receptor F5 (ADGRF5) is involved inthe neoplastic
transformation of some cancer types. However, the significance of ADGRF5 expression …

[HTML][HTML] Long non-coding RNA ABHD11-AS1 promotes colorectal cancer progression and invasion through targeting the integrin subunit alpha 5/focal adhesion …

J Luo, Y Jiang, L Wu, D Zhuo, S Zhang, X Jiang… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Long non-coding (lnc) RNA ABHD11-AS1 participates in the development and progress of
various cancers, but its role in colorectal cancer (CRC) remains poorly known. In the present …