A practical guide to methods controlling false discoveries in computational biology
Background In high-throughput studies, hundreds to millions of hypotheses are typically
tested. Statistical methods that control the false discovery rate (FDR) have emerged as …
tested. Statistical methods that control the false discovery rate (FDR) have emerged as …
MultipleTesting. com: A tool for life science researchers for multiple hypothesis testing correction
O Menyhart, B Weltz, B Győrffy - PloS one, 2021 - journals.plos.org
Scientists from nearly all disciplines face the problem of simultaneously evaluating many
hypotheses. Conducting multiple comparisons increases the likelihood that a non-negligible …
hypotheses. Conducting multiple comparisons increases the likelihood that a non-negligible …
Multiple testing with the structure-adaptive Benjamini–Hochberg algorithm
In multiple-testing problems, where a large number of hypotheses are tested simultaneously,
false discovery rate (FDR) control can be achieved with the well-known Benjamini …
false discovery rate (FDR) control can be achieved with the well-known Benjamini …
Adaptive novelty detection with false discovery rate guarantee
Adaptive novelty detection with false discovery rate guarantee Page 1 The Annals of Statistics
2024, Vol. 52, No. 1, 157–183 https://doi.org/10.1214/23-AOS2338 © Institute of Mathematical …
2024, Vol. 52, No. 1, 157–183 https://doi.org/10.1214/23-AOS2338 © Institute of Mathematical …
Conditional calibration for false discovery rate control under dependence
Conditional calibration for false discovery rate control under dependence Page 1 The Annals of
Statistics 2022, Vol. 50, No. 6, 3091–3118 https://doi.org/10.1214/21-AOS2137 © Institute of …
Statistics 2022, Vol. 50, No. 6, 3091–3118 https://doi.org/10.1214/21-AOS2137 © Institute of …
Integrative conformal p-values for out-of-distribution testing with labelled outliers
This paper presents a conformal inference method for out-of-distribution testing that
leverages side information from labelled outliers, which are commonly underutilized or even …
leverages side information from labelled outliers, which are commonly underutilized or even …
Integrative conformal p-values for powerful out-of-distribution testing with labeled outliers
This paper develops novel conformal methods to test whether a new observation was
sampled from the same distribution as a reference set. Blending inductive and transductive …
sampled from the same distribution as a reference set. Blending inductive and transductive …
Clipper: p-value-free FDR control on high-throughput data from two conditions
High-throughput biological data analysis commonly involves identifying features such as
genes, genomic regions, and proteins, whose values differ between two conditions, from …
genes, genomic regions, and proteins, whose values differ between two conditions, from …
Slotting metabolomics into routine precision medicine
Introduction Despite an impressive amount of metabolomics studies in animal models and
humans, most findings have not yet translated into the clinical setting, and the road ahead …
humans, most findings have not yet translated into the clinical setting, and the road ahead …
[PDF][PDF] Machine learning meets false discovery rate
The aim is to detect novelties, namely Xis with Pi= P0. This task is illustrated in Figure 1 on a
classical image data set, where we want to detect hand-written digit '9's in the test sample …
classical image data set, where we want to detect hand-written digit '9's in the test sample …