Mechanical stimuli have fundamental roles in articular cartilage during health and disease.
Chondrocytes respond to the physical properties of the cartilage extracellular matrix (ECM) …

Macrophages have long been known for their phagocytic capabilities and immune defence;
however, their role in healing is being increasingly recognized in recent years due to their …

Articular cartilage is a load‐bearing tissue playing a crucial mechanical role in diarthrodial
joints, facilitating joint articulation, and minimizing wear. The significance of biomechanical …

Biophysical cues play a key role in directing the lineage commitment of mesenchymal stem
cells or multipotent stromal cells (MSC s), but the mechanotransductive mechanisms at play …

The development of hydrogel-based biomaterials represents a promising approach to
generating new strategies for tissue engineering and regenerative medicine. In order to …

The control of stem cell response in vitro, including self‐renewal and lineage commitment,
has been proved to be directed by mechanical cues, even in the absence of biochemical …

Joint-derived stem cells are a promising alternative cell source for cartilage repair therapies
that may overcome many of the problems associated with the use of primary chondrocytes …

Stem cells demonstrate considerable promise for various preclinical and clinical
applications, including drug screening, disease treatments, and regenerative medicine …

Mesenchymal stromal cell (MSC)-based cell therapy in acute respiratory diseases is based
on MSC secretion of paracrine factors. Several strategies have proposed to improve this are …

Chondrogenesis of dedifferentiated chondrocytes and mesenchymal stem cells is influenced
not only by soluble molecules like growth factors, but also by the cell environment itself. The …