Ontogeny of tissue-resident macrophages
The origin of tissue-resident macrophages, crucial for homeostasis and immunity, has
remained controversial until recently. Originally described as part of the mononuclear …
remained controversial until recently. Originally described as part of the mononuclear …
Hematopoiesis: an evolving paradigm for stem cell biology
Establishment and maintenance of the blood system relies on self-renewing hematopoietic
stem cells (HSCs) that normally reside in small numbers in the bone marrow niche of adult …
stem cells (HSCs) that normally reside in small numbers in the bone marrow niche of adult …
[HTML][HTML] Distinct sources of hematopoietic progenitors emerge before HSCs and provide functional blood cells in the mammalian embryo
KE McGrath, JM Frame, KH Fegan, JR Bowen… - Cell reports, 2015 - cell.com
Hematopoietic potential arises in mammalian embryos before adult-repopulating
hematopoietic stem cells (HSCs). At embryonic day 9.5 (E9. 5), we show the first murine …
hematopoietic stem cells (HSCs). At embryonic day 9.5 (E9. 5), we show the first murine …
Tracing haematopoietic stem cell formation at single-cell resolution
Haematopoietic stem cells (HSCs) are derived early from embryonic precursors, such as
haemogenic endothelial cells and pre-haematopoietic stem cells (pre-HSCs), the molecular …
haemogenic endothelial cells and pre-haematopoietic stem cells (pre-HSCs), the molecular …
Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines
SJ Kattman, AD Witty, M Gagliardi, NC Dubois… - Cell stem cell, 2011 - cell.com
Efficient differentiation of embryonic stem cells (ESCs) and induced pluripotent stem cells
(iPSCs) to a variety of lineages requires step-wise approaches replicating the key …
(iPSCs) to a variety of lineages requires step-wise approaches replicating the key …
[HTML][HTML] SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
To improve our ability to identify hematopoietic stem cells (HSCs) and their localization in
vivo, we compared the gene expression profiles of highly purified HSCs and non-self …
vivo, we compared the gene expression profiles of highly purified HSCs and non-self …
Insights into endothelial progenitor cells: origin, classification, potentials, and prospects
H Chopra, MK Hung, DL Kwong… - Stem cells …, 2018 - Wiley Online Library
With the discovery of endothelial progenitor cells (EPCs) in the late 1990s, a paradigm shift
in the concept of neoangiogenesis occurred. The identification of circulating EPCs in …
in the concept of neoangiogenesis occurred. The identification of circulating EPCs in …
Human haematopoietic stem cell development: from the embryo to the dish
Haematopoietic stem cells (HSCs) emerge during embryogenesis and give rise to the adult
haematopoietic system. Understanding how early haematopoietic development occurs is of …
haematopoietic system. Understanding how early haematopoietic development occurs is of …
Embryonic stem cell differentiation: emergence of a new era in biology and medicine
G Keller - Genes & development, 2005 - genesdev.cshlp.org
The discovery of mouse embryonic stem (ES) cells> 20 years ago represented a major
advance in biology and experimental medicine, as it enabled the routine manipulation of the …
advance in biology and experimental medicine, as it enabled the routine manipulation of the …
Human endothelial progenitor cells
MC Yoder - Cold Spring Harbor perspectives in …, 2012 - perspectivesinmedicine.cshlp.org
Human endothelial progenitor cells (EPCs) have been generally defined as circulating cells
that express a variety of cell surface markers similar to those expressed by vascular …
that express a variety of cell surface markers similar to those expressed by vascular …