Abstract P-glycoprotein (P-gp) is a drug efflux transporter that triggers doxorubicin (DOX)
resistance. In this review, we highlight the molecular avenues regulating P-gp, such as Nrf2 …

Green chemistry has been a growing multidisciplinary field in recent years showing great
promise in biomedical applications, especially for cancer therapy. Chitosan (CS) is an …

P-glycoprotein (P-gp) is crucial in the active transport of various substrates with diverse
structures out of cells, resulting in poor intestinal permeation and limited bioavailability …

Gold nanoparticles (AuNPs), as a kind of inorganic nanoparticle, have been gradually
recognized as one of the most promising nanomaterials, which is attributed to their unique …

The field of nanomedicines and nanomaterials has been rapidly developing with several
considerable breakthroughs in the treatment of cancer. However, some challenges may …

The prognosis of brain cancers such as glioblastoma remains poor despite numerous
advancements in the field of neuro-oncology. The presence of the blood brain barrier (BBB) …

Conventional strategies (Turkevich's, and modified Turkevich's methods) often synthesize
gold nanoparticles (AuNPs). These pathways produce AuNPs using toxic chemistries to …

A facile approach was established to fabricate the pH-responsive surface charge reversal
carboxymethyl chitosan-based drug delivery system for pH and reduction dual-responsive …

Doxorubicin (DOX) is widely used as a clinical first-line anti-cancer drug. However, its
clinical application is severely limited due to the lack of tumor specificity of the drug and …

Glucose deprivation, hydroxyl radical generation, photothermal ablation, and ferroptosis
induction-installed injectable hydrogel reactor was designed for multiple therapy of localized …