Non-natural folded polymers (foldamers) display considerable versatility, and the design of
such molecules is of great current interest. In this respect, peptidic foldamers are perhaps …

Foldamers are sequence-specific oligomers akin to peptides, proteins and oligonucleotides
that fold into well-defined three-dimensional structures. They offer the chemical biologist a …

Synthetic macromolecular antimicrobials are a highly promising class of therapeutics with
immense potential for combating multidrug resistant microbes. In contrast to conventional …

Over the past 20 years, the field of foldamers has rapidly increased. Many β-peptides have
already been described and shown interesting properties. γ-Peptides have more recently …

The entry of the SARS-CoV-2 virus into a human host cell begins with the interaction
between the viral spike protein (S protein) and human angiotensin-converting enzyme 2 …

The article presents a research that examines an iterative synthesis which was developed
for the benzoylurea oligomers by using monomer units, secondary amide and isocyanate …

New classes of α/γ-and β/γ-hybrid peptides have been synthesized with novel 12/10-and
11/13-mixed helical patterns, respectively. The α/γ-peptides were derived from the dipeptide …

Utilizing bromine‐free, direct C–H bond amidations we have synthesized a large variety of
adamantane amides. Depending on the precursors used these amides directly yield …

Peptides and proteins are molecular devices that can adopt specific folded and organized
structures for performing diverse functions in living systems. The formation of such tertiary …

The complexity of structure and function among biopolymers has inspired chemists to
extrapolate to non-natural analogues that are intended to emulate the natural archetypes.[1] …