Due to improved phenotyping and genetic characterization, the field of 'incurable'and
'blinding'inherited retinal diseases (IRDs) has moved substantially forward. Decades of …

Fundus autofluorescence (FAF) imaging is an in vivo imaging method that allows for
topographic mapping of naturally or pathologically occurring intrinsic fluorophores of the …

Inherited retinal diseases (IRD) are a leading cause of blindness in the working age
population and children. The scope of this review is to familiarise clinicians and scientists …

ABCA4 is a member of the superfamily of ATP-binding cassette (ABC) transporters that is
preferentially localized along the rim region of rod and cone photoreceptor outer segment …

With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Macular dystrophies (MDs) consist of a heterogeneous group of disorders that are
characterised by bilateral symmetrical central visual loss. Advances in genetic testing over …

Objectives To evaluate the long‐term biosafety and efficacy of transplantation of human
embryonic stem cells‐derived retinal pigment epithelial (hESC‐RPE) cells in early‐stage of …

Major advances in the study of inherited retinal diseases (IRDs) have placed efforts to
develop treatments for these blinding conditions at the forefront of the emerging field of …

Fundus autofluorescence (FAF) has allowed in vivo mapping of retinal metabolic
derangements and structural changes not possible with conventional color imaging. Incident …

Stargardt disease (STGD1) is an autosomal recessive retinal dystrophy, characterised by
bilateral progressive central vision loss and subretinal deposition of lipofuscin‐like …