Compulsion is a cardinal symptom of drug addiction (severe substance use disorder).
However, compulsion is observed in only a small proportion of individuals who repeatedly …

The ability to make decisions and act quickly without hesitation can be advantageous in
many settings. However, when persistently expressed, impulsive decisions and actions are …

A decade ago, we hypothesized that drug addiction can be viewed as a transition from
voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by …

A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

Serotonin regulates a wide variety of brain functions and behaviors. Here, we synthesize
previous findings that serotonin regulates executive function, sensory gating, and social …

Executive function (EF), which refers to the more deliberate, top‐down neurocognitive
processes involved in self‐regulation, develops most rapidly during the preschool years …

Adolescence is characterized by making risky decisions. Early lesion and neuroimaging
studies in adults pointed to the ventromedial prefrontal cortex and related structures as …

We revisit our hypothesis that drug addiction can be viewed as the endpoint of a series of
transitions from initial voluntarily drug use to habitual, and ultimately compulsive drug use …

Despite significant theoretical advancement in the area of child neuropsychology, limited
attention has been paid to the developmental features of adolescence. The present study …

It has long been hypothesized that conditioning mechanisms play major roles in addiction.
Specifically, the associations between rewarding properties of drugs of abuse and the drug …