Metabolic reprogramming is a hallmark of cancer. However, mechanisms underlying
metabolic reprogramming and how altered metabolism in turn enhances tumorigenicity are …

The establishment and maintenance of peripheral T cells is important to ensure appropriate
immunity. In mammals, T cells are produced in the thymus before seeding the periphery …

Maintenance of cell population size is fundamental to the proper functioning of multicellular
organisms. Here, we describe a cell-intrinsic cell density–sensing pathway that enabled T …

To defend ourselves from invading pathogens, we are all equipped with an immune system,
a complex network of cells and proteins. The skin already provides a first layer of defense …