Several studies have demonstrated the anti-inflammatory potential of mesenchymal stromal
cells (MSCs) isolated from bone marrow, adipose tissue, placenta, and other sources …

During the past decade there has been significant progress made in understanding how
environmental agents, drugs, certain chemicals present in the diet, and occupational agents …

Regulatory B cells (Bregs) play a critical role in the control of autoimmunity and
inflammation. IL-10 production is the hallmark for the identification of Bregs. However, the …

NF-κB/Rel transcription factors regulate many genes involved in control of cellular
proliferation, neoplastic transformation, and apoptosis, including the c-myc oncogene …

The polycyclic aromatic hydrocarbon, 7, 12-dimethylbenz [a] anthracene (DMBA), is an
immunosuppressor as well as a potent organ-specific carcinogen. To understand the organ …

Much of what is known about the Aryl Hydrocarbon Receptor (AhR) centers on its ability to
mediate the deleterious effects of the environmental toxicant 2, 3, 7, 8-tetrachlorodibenzo-p …

Nearly a quarter of the total number of deaths in the world are caused by unhealthy living or
working environments. Therefore, we consider it significant to introduce the effect of a widely …

Polycyclic aromatic hydrocarbons (PAHs) such as benzo (a) pyrene (BP) are environmental
carcinogens exhibiting potent immunosuppressive properties. To determine the cellular …

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor historically
studied for its role in environmental chemical-mediated toxicity and carcinogenicity. In the …

2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD; dioxin), the prototype agonist of the aromatic
hydrocarbon (Ah) receptor, is a potent tumor promoter as well as a complete liver …