It is well established that maternal age is associated with a rapid decline in the production of
healthy and high-quality oocytes resulting in reduced fertility in women older than 35 years …

Recombination, the exchange of DNA between maternal and paternal chromosomes during
meiosis, is an essential feature of sexual reproduction in nearly all multicellular organisms …

Recombination is a central biological process with implications for many areas in the life
sciences. Yet we are only beginning to appreciate variation in the recombination rate along …

In humans, males have lower recombination rates than females over the majority of the
genome, but the opposite is usually true near the telomeres. These broad-scale differences …

Purpose To clarify the associations of the maternal age, history of miscarriage, and
embryonic/fetal size at miscarriage with the frequencies and profiles of cytogenetic …

BACKGROUND Meiotic chromosome segregation in human oocytes is notoriously error-
prone, especially with ageing. Such errors markedly reduce the reproductive chances of …

Aneuploidy is extremely high in aged human oocytes. Its cellular origin has been elusive.
Trisomy data implicate predominantly meiosis I errors in the genesis of oocyte aneuploidy …

Social insects have the highest rates of meiotic recombination among Metazoa, but there is
considerable variation within the Hymenoptera. We synthesize the literature to investigate …

Follicular microenvironment is paramount in the acquisition of oocyte competence, which is
dependent on two interconnected and interdependent processes: nuclear and cytoplasmic …

Highlights•Meiotic crossover (CO) frequency is under homeostatic control.•Meiotic CO
frequency can be modulated by extrinsic factors, such as temperature.•The synaptonemal …