Advances in plant molecular farming

OO Obembe, JO Popoola, S Leelavathi… - Biotechnology advances, 2011 - Elsevier
Plant molecular farming (PMF) is a new branch of plant biotechnology, where plants are
engineered to produce recombinant pharmaceutical and industrial proteins in large …

Plants as bioreactors: recent developments and emerging opportunities

AK Sharma, MK Sharma - Biotechnology advances, 2009 - Elsevier
In recent years, the use of plants as bioreactors has emerged as an exciting area of research
and significant advances have created new opportunities. The driving forces behind the …

Genetic diversity in tomato (Solanum lycopersicum) and its wild relatives

G Bauchet, M Causse - Genetic diversity in plants, 2012 - books.google.com
Tomato, ranking 1st in the world for vegetables, accounts for 14% of world vegetable
production (over 100 million metric tons/year $1.6 billion market;(Food and Agriculture …

Plants as bioreactors for the production of vaccine antigens

S Tiwari, PC Verma, PK Singh, R Tuli - Biotechnology advances, 2009 - Elsevier
Plants have been identified as promising expression systems for commercial production of
vaccine antigens. In phase I clinical trials several plant-derived vaccine antigens have been …

Improving protein quantity and quality—The next level of plant molecular farming

H Liu, MP Timko - International Journal of Molecular Sciences, 2022 - mdpi.com
Plants offer several unique advantages in the production of recombinant pharmaceuticals for
humans and animals. Although numerous recombinant proteins have been expressed in …

Recombinant plant-derived pharmaceutical proteins: current technical and economic bottlenecks

M Sabalza, P Christou, T Capell - Biotechnology letters, 2014 - Springer
Molecular pharming is a cost-effective platform for the production of recombinant proteins in
plants. Although the biopharmaceutical industry still relies on a small number of …

Effects of intestinal microbiota on physiological metabolism and pathogenicity of Vibrio

H Sun, C Zhu, X Fu, S Khattak, J Wang, Z Liu… - Frontiers in …, 2022 - frontiersin.org
Vibrio species are disseminated broadly in the marine environment. Some of them can
cause severe gastroenteritis by contaminating seafood and drinking water, such as Vibrio …

The use of plants for the production of therapeutic human peptides

C Lico, L Santi, RM Twyman, M Pezzotti, L Avesani - Plant cell reports, 2012 - Springer
Peptides have unique properties that make them useful drug candidates for diverse
indications, including allergy, infectious disease and cancer. Some peptides are intrinsically …

Recent advances and safety issues of transgenic plant-derived vaccines

Z Guan, B Guo, Y Huo, Z Guan, J Dai, Y Wei - Applied microbiology and …, 2013 - Springer
Transgenic plant-derived vaccines comprise a new type of bioreactor that combines plant
genetic engineering technology with an organism's immunological response. This …

Optimizing the yield of recombinant pharmaceutical proteins in plants

RM Twyman, S Schillberg… - Current Pharmaceutical …, 2013 - ingentaconnect.com
The production of recombinant pharmaceutical proteins in plants is entering a new phase
with the recent approval of recombinant glucocerebrosidase produced in carrot cells and the …