Protein analysis by shotgun/bottom-up proteomics
According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …
Human body fluid proteome analysis
The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …
Detection of serum hepcidin in renal failure and inflammation by using ProteinChip System
N Tomosugi, H Kawabata, R Wakatabe, M Higuchi… - Blood, 2006 - ashpublications.org
Hepcidin, a key regulator of iron metabolism, is expressed in the liver, distributed in blood,
and excreted in urine. However, to date, no reliable and practical method for measuring the …
and excreted in urine. However, to date, no reliable and practical method for measuring the …
Sample preparation for serum/plasma profiling and biomarker identification by mass spectrometry
JL Luque-Garcia, TA Neubert - Journal of Chromatography A, 2007 - Elsevier
In this article, we present an overview of the different strategies for sample preparation for
identification by mass spectrometry (MS) of biomarkers from serum and/or plasma. We …
identification by mass spectrometry (MS) of biomarkers from serum and/or plasma. We …
Investigation of an albumin‐enriched fraction of human serum and its albuminome
RL Gundry, Q Fu, CA Jelinek… - PROTEOMICS …, 2007 - Wiley Online Library
The removal of albumin and other high abundance proteins is a routine first step in the
analysis of serum and plasma proteomes. However, as albumin can bind proteins and …
analysis of serum and plasma proteomes. However, as albumin can bind proteins and …
Proteomics: from basic research to diagnostic application. A review of requirements & needs
F Vitzthum, F Behrens, NL Anderson… - Journal of proteome …, 2005 - ACS Publications
For several years proteomics research has been expected to lead to the finding of new
markers that will translate into clinical tests applicable to samples such as serum, plasma …
markers that will translate into clinical tests applicable to samples such as serum, plasma …
Diagnostic potential of tear proteomic patterns in Sjögren's syndrome
N Tomosugi, K Kitagawa, N Takahashi… - Journal of proteome …, 2005 - ACS Publications
Histological and functional changes of the lacrimal gland might be reflected in proteomic
patterns in tear fluids. In this study, we carried out a determination of the disease biomarkers …
patterns in tear fluids. In this study, we carried out a determination of the disease biomarkers …
Cardiovascular proteomics: tools to develop novel biomarkers and potential applications
Proteomics is the new systems biological approach to the study of proteins and protein
variation on a large scale as a result of biological processes and perturbations. The field is …
variation on a large scale as a result of biological processes and perturbations. The field is …
Multidimensional protein identification technology (MudPIT): technical overview of a profiling method optimized for the comprehensive proteomic investigation of …
T Kislinger, AO Gramolini… - Journal of the …, 2005 - ACS Publications
An optimized analytical expression profiling strategy based on gel-free multidimensional
protein identification technology (MudPIT) is reported for the systematic investigation of …
protein identification technology (MudPIT) is reported for the systematic investigation of …
New frontiers in proteomics research: a perspective
V Dhingra, M Gupta, T Andacht, ZF Fu - International journal of …, 2005 - Elsevier
Substantial advances have been made in the fundamental understanding of human biology,
ranging from DNA structure to identification of diseases associated with genetic …
ranging from DNA structure to identification of diseases associated with genetic …