Evolution of glutamatergic signaling and synapses
Glutamate (Glu) is the primary excitatory transmitter in the mammalian brain. But, we know
little about the evolutionary history of this adaptation, including the selection of l-glutamate …
little about the evolutionary history of this adaptation, including the selection of l-glutamate …
Targeting calcium homeostasis and impaired inter-organelle crosstalk as a potential therapeutic approach in Parkinson's disease
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the
loss of dopaminergic neurons in the substantia nigra pars compacta, leading to motor …
loss of dopaminergic neurons in the substantia nigra pars compacta, leading to motor …
Syncytial nerve net in a ctenophore adds insights on the evolution of nervous systems
P Burkhardt, J Colgren, A Medhus, L Digel, B Naumann… - Science, 2023 - science.org
A fundamental breakthrough in neurobiology has been the formulation of the neuron
doctrine by Santiago Ramón y Cajal, which stated that the nervous system is composed of …
doctrine by Santiago Ramón y Cajal, which stated that the nervous system is composed of …
Neuron–glia interaction in the Drosophila nervous system
J Bittern, N Pogodalla, H Ohm, L Brüser… - Developmental …, 2021 - Wiley Online Library
Animals are able to move and react in manifold ways to external stimuli. Thus,
environmental stimuli need to be detected, information must be processed, and, finally, an …
environmental stimuli need to be detected, information must be processed, and, finally, an …
Neuropeptidergic integration of behavior in Trichoplax adhaerens, an animal without synapses
A Senatore, TS Reese… - Journal of Experimental …, 2017 - journals.biologists.com
Trichoplax adhaerens is a flat, millimeter-sized marine animal that adheres to surfaces and
grazes on algae. Trichoplax displays a repertoire of different feeding behaviors despite the …
grazes on algae. Trichoplax displays a repertoire of different feeding behaviors despite the …
In vivo neuromodulation of animal behavior with organic semiconducting oligomers
Modulating neural activity with electrical or chemical stimulus can be used for fundamental
and applied research. Typically, neuronal stimulation is performed with intracellular and …
and applied research. Typically, neuronal stimulation is performed with intracellular and …
Sensing the world and its dangers: an evolutionary perspective in neuroimmunology
Detecting danger is key to the survival and success of all species. Animal nervous and
immune systems cooperate to optimize danger detection. Preceding studies have …
immune systems cooperate to optimize danger detection. Preceding studies have …
Coherent directed movement toward food modeled in Trichoplax, a ciliated animal lacking a nervous system
CL Smith, TS Reese, T Govezensky… - Proceedings of the …, 2019 - National Acad Sciences
Trichoplax adhaerens is a small, ciliated marine animal that glides on surfaces grazing upon
algae, which it digests externally. It has no muscles or nervous system and only six cell …
algae, which it digests externally. It has no muscles or nervous system and only six cell …
Sodium action potentials in placozoa: Insights into behavioral integration and evolution of nerveless animals
Placozoa are small disc-shaped animals, representing the simplest known, possibly
ancestral, organization of free-living animals. With only six morphological distinct cell types …
ancestral, organization of free-living animals. With only six morphological distinct cell types …
Evolutionary Analysis of Cnidaria Small Cysteine-Rich Proteins (SCRiPs), an Enigmatic Neurotoxin Family from Stony Corals and Sea Anemones (Anthozoa …
RA Barroso, L Ramos, H Moreno, A Antunes - Toxins, 2024 - mdpi.com
Cnidarians (corals, sea anemones, and jellyfish) produce toxins that play central roles in key
ecological processes, including predation, defense, and competition, being the oldest extant …
ecological processes, including predation, defense, and competition, being the oldest extant …