Progress of microfluidic hydrogel‐based scaffolds and organ‐on‐chips for the cartilage tissue engineering
Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …
the globe. Numerous approaches have been employed to treat cartilage diseases …
Microfluidic integration of regeneratable electrochemical affinity-based biosensors for continual monitoring of organ-on-a-chip devices
Organs-on-chips have emerged as viable platforms for drug screening and personalized
medicine. While a wide variety of human organ-on-a-chip models have been developed …
medicine. While a wide variety of human organ-on-a-chip models have been developed …
Microfluidic tissue engineering and bio‐actuation
Bio‐hybrid technologies aim to replicate the unique capabilities of biological systems that
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …
[HTML][HTML] Recent advances in the fabrication and application of biopolymer-based micro-and nanostructures: A comprehensive review
M Stanisz, Ł Klapiszewski, T Jesionowski - Chemical Engineering Journal, 2020 - Elsevier
The main focus of this review is recent advances in the preparation of bio-based
nanostructures. The structures especially prepared from natural resources have recently …
nanostructures. The structures especially prepared from natural resources have recently …
A comprehensive review on 3D tissue models: Biofabrication technologies and preclinical applications
R Xie, V Pal, Y Yu, X Lu, M Gao, S Liang, M Huang… - Biomaterials, 2023 - Elsevier
The limitations of traditional two-dimensional (2D) cultures and animal testing, when it
comes to precisely foreseeing the toxicity and clinical effectiveness of potential drug …
comes to precisely foreseeing the toxicity and clinical effectiveness of potential drug …
Recapitulating monocyte extravasation to the synovium in an organotypic microfluidic model of the articular joint
C Mondadori, S Palombella, S Salehi, G Talo… - …, 2021 - iopscience.iop.org
The synovium of osteoarthritis (OA) patients can be characterized by an abnormal
accumulation of macrophages originating from extravasated monocytes. Since targeting …
accumulation of macrophages originating from extravasated monocytes. Since targeting …
Current advances in 3D dynamic cell culture systems
The traditional two-dimensional (2D) cell culture methods have a long history of mimicking in
vivo cell growth. However, these methods cannot fully represent physiological conditions …
vivo cell growth. However, these methods cannot fully represent physiological conditions …
[HTML][HTML] Organ-on-a-chip microengineering for bio-mimicking disease models and revolutionizing drug discovery
T Ahmed - Biosensors and Bioelectronics: X, 2022 - Elsevier
The core of the drug research and screening processes is predicting the effect of drugs prior
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …
to human clinical trials. Due to the 2D cell culture and animal models' poor predictability, the …
Overcoming the dependence on animal models for osteoarthritis therapeutics–the promises and prospects of in vitro models
Osteoarthritis (OA) is a musculoskeletal disease characterized by progressive degeneration
of osteochondral tissues. Current treatment is restricted to the reduction of pain and loss of …
of osteochondral tissues. Current treatment is restricted to the reduction of pain and loss of …
Bone-on-a-chip platforms and integrated biosensors: Towards advanced in vitro bone models with real-time biosensing
Bone diseases, such as osteoporosis and bone defects, often lead to structural and
functional deformities of the patient's body. Understanding the complicated pathophysiology …
functional deformities of the patient's body. Understanding the complicated pathophysiology …