Despite widespread reports that intranasal application of oxytocin has a variety of behavioral
effects, very little of the huge amounts applied intranasally appears to reach the …

Oxytocin, a hypothalamic hormone that is secreted directly into the brain and enters the
peripheral circulation through the posterior pituitary gland, regulates a range of physiologic …

Oxytocin (OT) is a potential treatment for multiple neuropsychiatric disorders. As OT is a
peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies …

Obesity and its associated complications have reached epidemic proportions in the USA
and also worldwide, highlighting the need for new and more effective treatments. Although …

Results: Oxytocin markedly reduced hunger-driven food intake in the fasted state in obese
but not in normal-weight men, and led to a reduction in snack consumption in both groups …

The fact that more than 78 million adults in the US are considered overweight or obese
highlights the need to develop new, effective strategies to treat obesity and its associated …

Background Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction,
characterized by cognitive and memory impairments closely linked to hippocampal …

Based largely on a number of short-term administration studies, growing evidence suggests
that central oxytocin is important in the regulation of energy balance. The goal of the current …

The neuropeptide oxytocin has emerged as a promising pharmacotherapy for
methamphetamine (METH) addiction, and clinical trials of intranasal oxytocin are underway …

In addition to its pivotal role in psychosocial behavior, the hypothalamic neuropeptide
oxytocin contributes to metabolic control by suppressing eating behavior. Its involvement in …