Biofilms and vulvovaginal candidiasis
C Rodríguez-Cerdeira, MC Gregorio… - Colloids and Surfaces B …, 2019 - Elsevier
Candida species, including C. albicans, are part of the mucosal flora of most healthy women,
and inhabit the gastrointestinal and genitourinary tracts. Under favourable conditions, they …
and inhabit the gastrointestinal and genitourinary tracts. Under favourable conditions, they …
[HTML][HTML] Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata
KR Healey, DS Perlin - Journal of fungi, 2018 - mdpi.com
Candida glabrata has thoroughly adapted to successfully colonize human mucosal
membranes and survive in vivo pressures. prior to and during antifungal treatment. Out of all …
membranes and survive in vivo pressures. prior to and during antifungal treatment. Out of all …
Bacterial-fungal metabolic interactions within the microbiota and their potential relevance in human health and disease: a short review
A Lapiere, ML Richard - Gut Microbes, 2022 - Taylor & Francis
The composition of the microbiota is the focus of many recent publications describing the
effects of the microbiota on host health. In recent years, research has progressed further …
effects of the microbiota on host health. In recent years, research has progressed further …
[HTML][HTML] Nine Things Genomics Can Tell Us About Candida auris
Candida auris is a recently emerged multidrug-resistant fungal pathogen causing severe
illness in hospitalized patients. C. auris is most closely related to a few environmental or …
illness in hospitalized patients. C. auris is most closely related to a few environmental or …
Emerging new targets for the treatment of resistant fungal infections
N Liu, J Tu, G Dong, Y Wang… - Journal of medicinal …, 2018 - ACS Publications
With the increasing morbidity and mortality of invasive fungal infections and the emergence
of severe antifungal drug resistance, new drug targets and novel antifungal agents are …
of severe antifungal drug resistance, new drug targets and novel antifungal agents are …
BET–HDAC dual inhibitors for combinational treatment of breast cancer and concurrent candidiasis
Y Huang, N Liu, Z Pan, Z Li… - Journal of Medicinal …, 2023 - ACS Publications
Breast cancer is susceptible to Candida infections, and candidiasis has an enhancing effect
on the progression and metastasis of tumor. Breast cancer and concurrent candidiasis …
on the progression and metastasis of tumor. Breast cancer and concurrent candidiasis …
Discovery of BRD4–HDAC Dual Inhibitors with Improved Fungal Selectivity and Potent Synergistic Antifungal Activity against Fluconazole-Resistant Candida albicans
Z Li, Y Huang, J Tu, W Yang, N Liu… - Journal of Medicinal …, 2023 - ACS Publications
Over the past several decades, invasive fungal infections, especially candidiasis, have
caused dramatic morbidity and mortality due to ineffective antifungal drugs and severe drug …
caused dramatic morbidity and mortality due to ineffective antifungal drugs and severe drug …
Heat shock protein 90 (Hsp90)/Histone deacetylase (HDAC) dual inhibitors for the treatment of azoles-resistant Candida albicans
C Li, J Tu, G Han, N Liu, C Sheng - European journal of medicinal chemistry, 2022 - Elsevier
Clinical treatment of candidiasis has suffered from increasingly severe drug resistance and
limited efficacy. Thus, novel strategies to deal with drug resistance are highly desired to …
limited efficacy. Thus, novel strategies to deal with drug resistance are highly desired to …
Novel carboline fungal histone deacetylase (HDAC) inhibitors for combinational treatment of azole-resistant candidiasis
Z Li, J Tu, G Han, N Liu, C Sheng - Journal of Medicinal Chemistry, 2020 - ACS Publications
Due to the evolution and development of antifungal drug resistance, limited efficacy of
existing drugs has led to high mortality in patients with serious fungal infections. To develop …
existing drugs has led to high mortality in patients with serious fungal infections. To develop …
Discovery of novel fungal lanosterol 14α-demethylase (CYP51)/histone deacetylase dual inhibitors to treat azole-resistant candidiasis
G Han, N Liu, C Li, J Tu, Z Li… - Journal of medicinal …, 2020 - ACS Publications
Invasive fungal infections (particularly candidiasis) are emerging as severe infectious
diseases worldwide. Because of serious antifungal drug resistance, therapeutic efficacy of …
diseases worldwide. Because of serious antifungal drug resistance, therapeutic efficacy of …