[HTML][HTML] Atherosclerosis fate in the era of tailored functional foods: Evidence-based guidelines elicited from structure-and ligand-based approaches

L Azevedo, MSM Serafim, VG Maltarollo… - Trends in Food Science …, 2022 - Elsevier
Background Atherosclerosis is the primary cause of cardiovascular diseases (CVDs),
contributing to more than 33% of the annual deaths globally. Westernized dietary patterns, a …

[HTML][HTML] Vulnerable atherosclerotic plaque: is there a molecular signature?

RM Chiorescu, M Mocan, AI Inceu, AP Buda… - International Journal of …, 2022 - mdpi.com
Atherosclerosis and its clinical manifestations, coronary and cerebral artery diseases, are
the most common cause of death worldwide. The main pathophysiological mechanism for …

Sirtuins in macrophage immune metabolism: A novel target for cardiovascular disorders

C Xu, J Li, Z Liang, Y Zhong, Z Zhang, X Hu… - International Journal of …, 2023 - Elsevier
Abstract Sirtuins (SIRT1-SIRT7), as a family of NAD+-dependent protein modifying enzymes,
have various catalytic functions, such as deacetylases, dealkalylases, and deribonucleases …

[HTML][HTML] Key chemokine pathways in atherosclerosis and their therapeutic potential

AB Márquez, EPC van der Vorst, SL Maas - Journal of Clinical Medicine, 2021 - mdpi.com
The search to improve therapies to prevent or treat cardiovascular diseases (CVDs) rages
on, as CVDs remain a leading cause of death worldwide. Here, the main cause of CVDs …

Surface-modified nanotherapeutics targeting atherosclerosis

W Li, KM Gonzalez, J Chung, M Kim, J Lu - Biomaterials science, 2022 - pubs.rsc.org
Atherosclerosis is a chronic and metabolic-related disease that is a serious threat to human
health. Currently available diagnostic and therapeutic measures for atherosclerosis lack …

[HTML][HTML] Profile and functional prediction of plasma exosome-derived CircRNAs from acute ischemic stroke patients

J Yang, J Hao, Y Lin, Y Guo, K Liao, M Yang… - Frontiers in …, 2022 - frontiersin.org
Stroke is one of the major causes of death and long-term disability, of which acute ischemic
stroke (AIS) is the most common type. Although circular RNA (circRNA) expression profiles …

Gasdermin D-mediated pyroptosis promotes the development of atherosclerosis

B Huang, Z Zou, Y Li, H Chen, K Lai, Y Yuan… - Laboratory …, 2024 - Elsevier
Atherosclerosis is a chronic inflammatory cardiovascular disease with a high-morbidity and
mortality rate. An increasing number of studies have addressed the crucial contribution of …

[HTML][HTML] Identification and Validation of Candidate Gene Module Along With Immune Cells Infiltration Patterns in Atherosclerosis Progression to Plaque Rupture via …

J Xu, C Chen, Y Yang - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Objective To explore the differentially expressed genes (DEGs) along with infiltrating
immune cells landscape and their potential mechanisms in the progression of …

Resveratrol protects against ox-LDL-induced endothelial dysfunction in atherosclerosis via depending on circ_0091822/miR-106b-5p-mediated upregulation of TLR4

J Chen, Y Liu, Y Liu, J Peng - Immunopharmacology and …, 2022 - Taylor & Francis
Background Atherosclerosis (AS) is the most common inducer of cardiovascular diseases,
and resveratrol (RSV) has played a protective function in the endothelial injury of AS. This …

Cyanidin-3-O-β-Glucoside Attenuates Platelet Chemokines and Their Receptors in Atherosclerotic Inflammation of ApoE–/– Mice

Y Yao, X Zhang, Y Xu, Y Zhao, F Song… - Journal of Agricultural …, 2022 - ACS Publications
Platelet chemokines play well-established roles in the atherosclerotic inflammation.
Cyanidin-3-O-β-glucoside (Cy-3-g) is one of the main bioactive compounds in anthocyanins …