[HTML][HTML] Antimicrobial peptides and their therapeutic potential for bacterial skin infections and wounds
A Pfalzgraff, K Brandenburg, G Weindl - Frontiers in pharmacology, 2018 - frontiersin.org
Alarming data about increasing resistance to conventional antibiotics are reported, while at
the same time the development of new antibiotics is stagnating. Skin and soft tissue …
the same time the development of new antibiotics is stagnating. Skin and soft tissue …
[HTML][HTML] Chemical modifications to increase the therapeutic potential of antimicrobial peptides
Y Han, M Zhang, R Lai, Z Zhang - Peptides, 2021 - Elsevier
The continued use of antibiotics has been accompanied by the rapid emergence and spread
of antibiotic-resistant strains of bacteria. Antimicrobial peptides (AMPs), also known as host …
of antibiotic-resistant strains of bacteria. Antimicrobial peptides (AMPs), also known as host …
[HTML][HTML] Antimicrobial peptides: mechanism of action, activity and clinical potential
QY Zhang, ZB Yan, YM Meng, XY Hong, G Shao… - Military Medical …, 2021 - Springer
The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …
COVID‐19: Proposing a Ketone‐Based Metabolic Therapy as a Treatment to Blunt the Cytokine Storm
PC Bradshaw, WA Seeds, AC Miller… - Oxidative Medicine …, 2020 - Wiley Online Library
Human SARS‐CoV‐2 infection is characterized by a high mortality rate due to some patients
developing a large innate immune response associated with a cytokine storm and acute …
developing a large innate immune response associated with a cytokine storm and acute …
Sensitizing Staphylococcus aureus to antibacterial agents by decoding and blocking the lipid flippase MprF
CJ Slavetinsky, JN Hauser, C Gekeler, J Slavetinsky… - Elife, 2022 - elifesciences.org
The pandemic of antibiotic resistance represents a major human health threat demanding
new antimicrobial strategies. Multiple peptide resistance factor (MprF) is the synthase and …
new antimicrobial strategies. Multiple peptide resistance factor (MprF) is the synthase and …
Advanced role of neutrophils in common respiratory diseases
J Liu, Z Pang, G Wang, X Guan, K Fang… - Journal of …, 2017 - Wiley Online Library
Respiratory diseases, always being a threat towards the health of people all over the world,
are most tightly associated with immune system. Neutrophils serve as an important …
are most tightly associated with immune system. Neutrophils serve as an important …
The LL-37 domain: A clue to cathelicidin immunomodulatory response?
ML Leite, HM Duque, GR Rodrigues, NB da Cunha… - Peptides, 2023 - Elsevier
Host defense peptides (HDPs) are naturally occurring polypeptide sequences that, in
addition to being active against bacteria, fungi, viruses, and other parasites, may stimulate …
addition to being active against bacteria, fungi, viruses, and other parasites, may stimulate …
Cathelicidin‐related antimicrobial peptide promotes neuroinflammation through astrocyte–microglia communication in experimental autoimmune encephalomyelitis
Cathelicidin‐related antimicrobial peptide (CRAMP) is an effector molecule of the innate
immune system with direct antimicrobial and immunomodulatory activities; however, its role …
immune system with direct antimicrobial and immunomodulatory activities; however, its role …
Extending the vitamin D pathway to vitamin D3 and CYP27A1 in periodontal ligament cells
C Zhang, K Liu, J Hou - Journal of Periodontology, 2021 - Wiley Online Library
Background In periodontal connective tissue cells, the vitamin D pathway has been
elucidated, and vitamin D3 in the main storage form, 25‐hydroxy vitamin D3 (25 [OH] D3) …
elucidated, and vitamin D3 in the main storage form, 25‐hydroxy vitamin D3 (25 [OH] D3) …
[HTML][HTML] Native pig neutrophil products: insights into their antimicrobial activity
E Fernández-De La Cruz, J Wessely-Szponder… - Microorganisms, 2023 - mdpi.com
Cationic antimicrobial peptides are molecules with potential applications for treating
infections due to their antimicrobial and immunomodulatory properties. The aim of this work …
infections due to their antimicrobial and immunomodulatory properties. The aim of this work …