Obstructive sleep apnoea (OSA) is a common disorder characterized by repetitive episodes
of nocturnal breathing cessation due to upper airway collapse. OSA causes severe …

Autonomic cardiovascular control changes across sleep stages. Thus, blood pressure (BP),
heart rate and peripheral vascular resistance progressively decrease in non-rapid eye …

Background The mechanisms by which mandibular advancement splints (MAS) improve
obstructive sleep apnoea (OSA) are not well understood. This study aimed to evaluate the …

Snoring is a prevalent disorder affecting 20–40% of the general population. The mechanism
of snoring is vibration of anatomical structures in the pharyngeal airway. Flutter of the soft …

Rationale: The efficacy of immediate adaptation of mandibular advancement devices made
of thermoplastic material as a treatment option for sleep-disordered breathing (SDB) has …

Mandibular advancement device (MAD) therapy is the most commonly used non-continuous
positive airway pressure (CPAP) treatment for obstructive sleep apnea (OSA). Although OSA …

Obstructive sleep apnea (OSA) is the most common respiratory disorder of sleep. The vast
majority (> 80%) of adults with moderate to severe OSA remain undiagnosed. The economic …

Background: Previous randomized controlled trials have addressed the efficacy of
mandibular advancement devices (MADs) in the treatment of obstructive sleep apnea (OSA) …

In clinical practice, oral appliances are used primarily for obstructive sleep apnea patients
who do not respond to continuous positive airway pressure (CPAP) therapy. We …

Background: Long-term trials are needed to capture information regarding the persistence of
efficacy and loss to follow-up of both mandibular advancement device (MAD) therapy and …