Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity
G Olmos, J Lladó - Mediators of inflammation, 2014 - Wiley Online Library
Tumor necrosis factor alpha (TNF‐α) is a proinflammatory cytokine that exerts both
homeostatic and pathophysiological roles in the central nervous system. In pathological …
homeostatic and pathophysiological roles in the central nervous system. In pathological …
[HTML][HTML] Effect of paraquat on cytotoxicity involved in oxidative stress and inflammatory reaction: A review of mechanisms and ecological implications
J Chen, Y Su, F Lin, M Iqbal, K Mehmood… - Ecotoxicology and …, 2021 - Elsevier
Paraquat (PQ) is a cheap and an effective herbicide, which is widely being used worldwide
to remove weeds in cultivated crop fields. However, it can cause soil and water pollution …
to remove weeds in cultivated crop fields. However, it can cause soil and water pollution …
A systematic review and meta-analysis of inflammatory biomarkers in Parkinson's disease
Y Qu, J Li, Q Qin, D Wang, J Zhao, K An, Z Mao… - npj Parkinson's …, 2023 - nature.com
Neuroinflammation plays a crucial role in the pathogenesis of Parkinson's disease (PD), but
controversies persist. Studies reporting concentrations of blood or cerebrospinal fluid (CSF) …
controversies persist. Studies reporting concentrations of blood or cerebrospinal fluid (CSF) …
MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration
C Cebrián, FA Zucca, P Mauri, JA Steinbeck… - Nature …, 2014 - nature.com
Subsets of rodent neurons are reported to express major histocompatibility complex class I
(MHC-I), but such expression has not been reported in normal adult human neurons. Here …
(MHC-I), but such expression has not been reported in normal adult human neurons. Here …
Cytokine dysregulation in autism spectrum disorders (ASD): possible role of the environment
PE Goines, P Ashwood - Neurotoxicology and teratology, 2013 - Elsevier
Autism spectrum disorders (ASD) are neurodevelopmental diseases that affect an alarming
number of individuals. The etiological basis of ASD is unclear, and evidence suggests it …
number of individuals. The etiological basis of ASD is unclear, and evidence suggests it …
Neuroinflammation and oxidative stress: co-conspirators in the pathology of Parkinson's disease
Parkinson's disease (PD) is a complex disease, with genetics and environment contributing
to the disease onset. Recent studies of causative PD genes have confirmed the involvement …
to the disease onset. Recent studies of causative PD genes have confirmed the involvement …
Occupational and environmental exposure to pesticides and cytokine pathways in chronic diseases
S Gangemi, E Gofita, C Costa… - International …, 2016 - spandidos-publications.com
Pesticides can exert numerous effects on human health as a consequence of both
environmental and occupational exposures. The available knowledge base suggests that …
environmental and occupational exposures. The available knowledge base suggests that …
Mutant LRRK2 mediates peripheral and central immune responses leading to neurodegeneration in vivo
E Kozina, S Sadasivan, Y Jiao, Y Dou, Z Ma, H Tan… - Brain, 2018 - academic.oup.com
Missense mutations in the leucine rich repeat kinase 2 (LRRK2) gene result in late-onset
Parkinson's disease. The incomplete penetrance of LRRK2 mutations in humans and …
Parkinson's disease. The incomplete penetrance of LRRK2 mutations in humans and …
Inflammation in Parkinson's disease
Parkinson's disease (PD) is a common neurodegenerative disease that is characterized by
the degeneration of dopaminergic neurons in the substantia nigra pars compacta …
the degeneration of dopaminergic neurons in the substantia nigra pars compacta …
Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress …
The organophosphate (OP) pesticide chlorpyrifos (CPF), used in agricultural settings,
induces developmental and neurological impairments. Recent studies using in vitro cell …
induces developmental and neurological impairments. Recent studies using in vitro cell …