In recent years, the number of studies investigating the impact of the gut microbiome in
colorectal cancer (CRC) has risen sharply. As a result, we now know that various microbes …

Colorectal cancer (CRC) is one of the most commonly diagnosed malignancies with a high
incidence and mortality rate. An essential challenge in colorectal cancer management is to …

Immune dysregulation plays a vital role in colorectal cancer initiation and progression. Long
noncoding RNAs (lncRNA) exhibit multiple functions including regulation of gene …

Colorectal cancer (CRC) is the third most common cancer and leading cause of cancer
related deaths worldwide. Despite recent advancements in surgical and molecular targeted …

Exosome-shuttled bioactive miRNAs act as novel non-invasive biomarkers for cancer
diagnosis have received increasing attention. In this study, we aimed to investigate the …

Although variation in gut microbiome composition has been linked with colorectal cancer
(CRC), the factors that mediate the interactions between CRC tumors and the microbiome …

Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. In more
than 90% of all CRC patients, the master oncogenic Ras‐Wnt signaling axis is over …

Evasion of apoptosis is a hallmark of cancer, which is frequently mediated by upregulation of
the antiapoptotic BCL-2 family proteins. In colorectal cancer (CRC), previous work has …

Tumor suppressor genes (TSGs) and oncogenes (OG) are involved in carcinogenesis.
MiRNAs also contribute to cellular pathways leading to cancer. We use data from 217 …

Background The nuclear factor-kappa B (NF-κB) signalling pathway is a regulator of immune
response and inflammation that has been implicated in the carcinogenic process. We …