Metabolomics, which is the profiling of metabolites in biofluids, cells and tissues, is routinely
applied as a tool for biomarker discovery. Owing to innovative developments in informatics …

Metabolomics generates a profile of small molecules that are derived from cellular
metabolism and can directly reflect the outcome of complex networks of biochemical …

Fructose consumption is linked to the rising incidence of obesity and cancer, which are two
of the leading causes of morbidity and mortality globally,. Dietary fructose metabolism …

METLIN originated as a database to characterize known metabolites and has since
expanded into a technology platform for the identification of known and unknown …

We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …

In addition to fatty acids, glucose and lactate are important myocardial substrates under
physiologic and stress conditions. They are metabolized to pyruvate, which enters …

It is well established that lactate secreted by fermenting cells can be oxidized or used as a
gluconeogenic substrate by other cells and tissues. It is generally assumed, however, that …

The greatest unmet needs in biomarker discovery are those discoveries that lead to the
development of clinical diagnostic tests. These clinical diagnostic tests can provide early …

Covering: up to 2021 Plants and their associated microbial communities are known to
produce millions of metabolites, a majority of which are still not characterized and are …

Metabolite identification represents a major challenge, and opportunity, for biochemistry.
The collective characterization and quantification of metabolites in living organisms, with its …