Tumoricidal photodynamic (PDT) and photothermal (PTT) therapies harness light to
eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen …

Effective treatment delivery in photodynamic therapy (PDT) requires coordination of the light
source, the photosensitizer, and the delivery device appropriate to the target tissue. Lasers …

Photodynamic therapy (PDT) is a clinically approved cancer therapy, based on a
photochemical reaction between a light activatable molecule or photosensitizer, light, and …

A significant mortality rate is associated with oral cancer, particularly in cases of late-stage
diagnosis. Since the last decades, oral cancer survival rates have only gradually improved …

This review follows the research, development and clinical applications of the
photosensitizer 5, 10, 15, 20‐tetra (m‐hydroxyphenyl) chlorin (m THPC, temoporfin) in …

Oral cancer is a global health burden with significantly poor survival, especially when the
diagnosis is at its late stage. Despite advances in current treatment modalities, there has …

Photochemical internalisation (PCI) is a unique intervention which involves the release of
endocytosed macromolecules into the cytoplasmic matrix. PCI is based on the use of …

Oral cavity and oropharyngeal carcinomas (oral cancer) represents a significant cause of
morbidity and mortality. Despite efforts in improving early diagnosis and treatment, the 5 …

Photodynamic therapy (PDT) has been under development for at least 40 years. Multiple
studies have demonstrated significant anti-tumor efficacy with limited toxicity concerns. PDT …

Advanced head and neck squamous cell carcinoma, after locoregional treatment and
multiple lines of systemic therapies, represents a great challenge to overcome acquired …