Technological innovations in photochemistry for organic synthesis: flow chemistry, high-throughput experimentation, scale-up, and photoelectrochemistry

L Buglioni, F Raymenants, A Slattery… - Chemical …, 2021 - ACS Publications
Photoinduced chemical transformations have received in recent years a tremendous amount
of attention, providing a plethora of opportunities to synthetic organic chemists. However …

Automated chemical oligosaccharide synthesis: novel approach to traditional challenges

M Panza, SG Pistorio, KJ Stine… - Chemical reviews, 2018 - ACS Publications
Advances in carbohydrate chemistry have certainly made common oligosaccharides much
more accessible. However, many current methods still rely heavily upon specialized …

[HTML][HTML] Advances in glycoside and oligosaccharide synthesis

CJ Crawford, PH Seeberger - Chemical Society Reviews, 2023 - pubs.rsc.org
The structural complexity of glycans poses a serious challenge in the chemical synthesis of
glycosides, oligosaccharides and glycoconjugates. Glycan complexity, determined by …

“One-pot” protection, glycosylation, and protection–glycosylation strategies of carbohydrates

SS Kulkarni, CC Wang, NM Sabbavarapu… - Chemical …, 2018 - ACS Publications
Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play
significant roles in a variety of vital biological processes. Access to unique and …

Automated glycan assembly: a perspective

M Guberman, PH Seeberger - Journal of the American Chemical …, 2019 - ACS Publications
The intrinsic complexity of carbohydrate structures has hampered access to pure glycans
and hence impeded progress in the glycosciences. Automated Glycan Assembly (AGA) has …

Toward automated enzymatic synthesis of oligosaccharides

L Wen, G Edmunds, C Gibbons, J Zhang… - Chemical …, 2018 - ACS Publications
Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …

The logic of automated glycan assembly

PH Seeberger - Accounts of Chemical Research, 2015 - ACS Publications
Conspectus Carbohydrates are the most abundant biopolymers on earth and part of every
living creature. Glycans are essential as materials for nutrition and for information transfer in …

[HTML][HTML] Infant formula supplemented with biotics: current knowledge and future perspectives

S Salminen, B Stahl, G Vinderola, H Szajewska - Nutrients, 2020 - mdpi.com
Breastfeeding is natural and the optimal basis of infant nutrition and development, with many
benefits for maternal health. Human milk is a dynamic fluid fulfilling an infant's specific …

Production of human milk oligosaccharides by enzymatic and whole-cell microbial biotransformations

GA Sprenger, F Baumgärtner, C Albermann - Journal of biotechnology, 2017 - Elsevier
Human milk oligosaccharides (HMO) are almost unique constituents of breast milk and are
not found in appreciable amounts in cow milk. Due to several positive aspects of HMO for …

Overcoming the limited availability of human milk oligosaccharides: challenges and opportunities for research and application

L Bode, N Contractor, D Barile, N Pohl… - Nutrition …, 2016 - academic.oup.com
Human milk oligosaccharides (HMOs) are complex sugars highly abundant in human milk
but currently not present in infant formula. Rapidly accumulating evidence from in vitro and …