Regulation of cisplatin resistance in bladder cancer by epigenetic mechanisms

F Li, Z Zheng, W Chen, D Li, H Zhang, Y Zhu… - Drug Resistance …, 2023 - Elsevier
Bladder cancer is one of the most common malignancies in the world. Cisplatin is one of the
most potent and widely used anticancer drugs and has been employed in several …

An epigenetic role of mitochondria in cancer

Y Liu, C Chen, X Wang, Y Sun, J Zhang, J Chen, Y Shi - Cells, 2022 - mdpi.com
Mitochondria are not only the main energy supplier but are also the cell metabolic center
regulating multiple key metaborates that play pivotal roles in epigenetics regulation. These …

Instability challenges and stabilization strategies of pharmaceutical proteins

M Akbarian, SH Chen - Pharmaceutics, 2022 - mdpi.com
Maintaining the structure of protein and peptide drugs has become one of the most important
goals of scientists in recent decades. Cold and thermal denaturation conditions …

Advances in enrichment methods for mass spectrometry-based proteomics analysis of post-translational modifications

J Brandi, R Noberini, T Bonaldi, D Cecconi - Journal of Chromatography A, 2022 - Elsevier
Post-translational modifications (PTMs) occur during or after protein biosynthesis and
increase the functional diversity of proteome. They comprise phosphorylation, acetylation …

Proteomics of post-translational modifications in colorectal cancer: Discovery of new biomarkers

G Zhu, L Jin, W Sun, S Wang, N Liu - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Colorectal cancer (CRC) is one of the costliest health problems and ranks second in cancer-
related mortality in developed countries. With the aid of proteomics, many protein …

Current trends in the analysis of post-translational modifications

D Virág, B Dalmadi-Kiss, K Vékey, L Drahos… - Chromatographia, 2020 - Springer
Post-translational modifications controlling a large number of biological functions are key
aspects of protein diversity. They have an important role controlling cellular processes and …

Effects of protein posttranslational modifications on meat quality: A review

X Li, D Zhang, C Ren, Y Bai, M Ijaz… - … Reviews in Food …, 2021 - Wiley Online Library
Meat quality plays an important role in the purchase decision of consumers, affecting
producers and retailers. The formation mechanisms determining meat quality are intricate …

Current methods of post-translational modification analysis and their applications in blood cancers

K Dunphy, P Dowling, D Bazou, P O'Gorman - Cancers, 2021 - mdpi.com
Simple Summary This review discusses current techniques used to study post-translational
protein modifications (PTMs) and their contribution to blood cancer research. Blood cancer …

What room for two-dimensional gel-based proteomics in a shotgun proteomics world?

K Marcus, C Lelong, T Rabilloud - Proteomes, 2020 - mdpi.com
Two-dimensional gel electrophoresis was instrumental in the birth of proteomics in the late
1980s. However, it is now often considered as an outdated technique for proteomics—a …

The functions and mechanisms of post-translational modification in protein regulators of RNA methylation: Current status and future perspectives

Y Chen, Z Jiang, Y Yang, C Zhang, H Liu… - International Journal of …, 2023 - Elsevier
RNA methylation, an epigenetic modification that does not alter gene sequence, may be
important to diverse biological processes. Protein regulators of RNA methylation include …