Transposable elements shape the evolution of mammalian development
AD Senft, TS Macfarlan - Nature Reviews Genetics, 2021 - nature.com
Transposable elements (TEs) promote genetic innovation but also threaten genome stability.
Despite multiple layers of host defence, TEs actively shape mammalian-specific …
Despite multiple layers of host defence, TEs actively shape mammalian-specific …
Viruses defined by the position of the virosphere within the replicator space
Originally, viruses were defined as miniscule infectious agents that passed through filters
that retain even the smallest cells. Subsequently, viruses were considered obligate …
that retain even the smallest cells. Subsequently, viruses were considered obligate …
Extracellular vesicles set the stage for brain plasticity and recovery by multimodal signalling
DM Hermann, L Peruzzotti-Jametti, B Giebel… - Brain, 2024 - academic.oup.com
Extracellular vesicles (EVs) are extremely versatile naturally occurring membrane particles
that convey complex signals between cells. EVs of different cellular sources are capable of …
that convey complex signals between cells. EVs of different cellular sources are capable of …
A functional dissection of the mRNA and locally synthesized protein population in neuronal dendrites and axons
JD Perez, CM Fusco, EM Schuman - Annual Review of Genetics, 2021 - annualreviews.org
Neurons are characterized by a complex morphology that enables the generation of
subcellular compartments with unique biochemical and biophysical properties, such as …
subcellular compartments with unique biochemical and biophysical properties, such as …
The molecular memory code and synaptic plasticity: A synthesis
SJ Gershman - Biosystems, 2023 - Elsevier
The most widely accepted view of memory in the brain holds that synapses are the storage
sites of memory, and that memories are formed through associative modification of …
sites of memory, and that memories are formed through associative modification of …
[HTML][HTML] Co-opting bacterial viruses for DNA exchange: structure and regulation of gene transfer agents
Horizontal gene transfer occurs via a range of mechanisms, including transformation,
conjugation and bacteriophage transduction. Gene transfer agents (GTAs) are an …
conjugation and bacteriophage transduction. Gene transfer agents (GTAs) are an …
Molecular physiology of Arc/Arg3. 1: The oligomeric state hypothesis of synaptic plasticity
MS Eriksen, CR Bramham - Acta Physiologica, 2022 - Wiley Online Library
The immediate early gene, Arc, is a pivotal regulator of synaptic plasticity, memory, and
cognitive flexibility. But what is Arc protein? How does it work? Inside the neuron, Arc is a …
cognitive flexibility. But what is Arc protein? How does it work? Inside the neuron, Arc is a …
Retrotransposons as drivers of mammalian brain evolution
Retrotransposons, a large and diverse class of transposable elements that are still active in
humans, represent a remarkable force of genomic innovation underlying mammalian …
humans, represent a remarkable force of genomic innovation underlying mammalian …
Phosphatidylinositol-3-phosphate mediates Arc capsid secretion through the multivesicular body pathway
Activity-regulated cytoskeleton-associated protein (Arc/Arg3. 1) is an immediate early gene
that plays a vital role in learning and memory. Arc protein has structural and functional …
that plays a vital role in learning and memory. Arc protein has structural and functional …