Naked mole-rats (NMRs, Heterocephalus glaber) are the longest-lived rodents with a
maximum life span exceeding 37 years. They exhibit a delayed aging phenotype and …

Cancer cell populations evolve by a stepwise process involving natural selection of the fittest
variants within a tissue ecosystem context and as modified by therapy. Genomic scrutiny of …

Naked mole‐rats (NMRs) have exceptional longevity and are resistant to age‐related
physiological decline and diseases. Given the role of cellular senescence in aging, we …

The neurobiological origins of social behaviors are incompletely understood. Here we
utilized synthetic biology approaches to reprogram the function of ZFP189, a transcription …

Our skin provides a physical and immunological barrier against dehydration and
environmental insults ranging from microbial attacks, toxins and UV irradiation to wounding …

The naked mole-rat (NMR) is a unique long-lived rodent which is highly resistant to age-
associated disorders and cancer. The immune system of NMR possesses a distinct cellular …

To maintain fertility, male mice re-repress transposable elements (TEs) that were de-
silenced in the early gonocytes before their differentiation into spermatogonia. However, the …

Certain mammalian species are resistant to cancer, and a better understanding of how this
cancer resistance arises could provide valuable insights for basic cancer research. Recent …

The naked mole-rat (NMR) Heterocephalus glaber (from the Greek/latin words ἕτερος,
heteros= divergent, κεφαλή, kephalē= head and glabra= hairless) was first described by …

Cellular senescence is a state of permanent proliferative arrest that occurs in response to
DNA damage-inducing endogenous and exogenous stresses, and is often accompanied by …