The most widespread intracellular bacteria in the animal kingdom are maternally inherited
endosymbionts of the genus Wolbachia. Their prevalence in arthropods and nematodes …

Dengue is caused by the dengue virus (DENVs) infection and clinical manifestations include
dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS) …

The class Alphaproteobacteria is comprised of a diverse assemblage of Gram-negative
bacteria that includes organisms of varying morphologies, physiologies and habitat …

Wolbachia are successful Gram-negative bacterial endosymbionts, globally infecting a large
fraction of arthropod species and filarial nematodes. Efficient vertical transmission, the …

Mosquitoes represent the major arthropod vectors of human disease worldwide transmitting
malaria, lymphatic filariasis, and arboviruses such as dengue virus and Zika virus …

Since the discovery of antimicrobial peptide responses 40 years ago, the fruit fly Drosophila
melanogaster has proven to be a powerful model for the study of innate immunity. Early work …

Insect guts present distinctive environments for microbial colonization, and bacteria in the
gut potentially provide many beneficial services to their hosts. Insects display a wide range …

Aedes mosquito-transmitted diseases, such as dengue, Zika and chikungunya, are
becoming major global health emergencies while old threats, such as yellow fever, are re …

Dengue fever is the most important mosquito-borne viral disease of humans with more than
50 million cases estimated annually in more than 100 countries,. Disturbingly, the …

The immune system probably evolved to limit the negative effects exerted by pathogens on
host homeostasis. This defence strategy relies on the concerted action of innate and …