[HTML][HTML] Biomarkers in schizophrenia: a focus on blood based diagnostics and theranostics

CY Lai, E Scarr, M Udawela, I Everall… - World journal of …, 2016 - ncbi.nlm.nih.gov
Identifying biomarkers that can be used as diagnostics or predictors of treatment response
(theranostics) in people with schizophrenia (Sz) will be an important step towards being able …

Implications for reactive oxygen species in schizophrenia pathogenesis

M Koga, AV Serritella, A Sawa, TW Sedlak - Schizophrenia research, 2016 - Elsevier
Oxidative stress is a well-recognized participant in the pathophysiology of multiple brain
disorders, particularly neurodegenerative conditions such as Alzheimer's and Parkinson's …

Oxidative stress and emergence of psychosis

V Rambaud, A Marzo, B Chaumette - Antioxidants, 2022 - mdpi.com
Treatment and prevention strategies for schizophrenia require knowledge about the
mechanisms involved in the psychotic transition. Increasing evidence suggests a redox …

Elevated serum levels of malondialdehyde and cortisol are associated with major depressive disorder: a case-control study

MR Islam, MR Islam, I Ahmed… - SAGE open …, 2018 - journals.sagepub.com
Objectives: Major depressive disorder is diagnosed on the basis of patient's self-reported
experiences, behavior reported by relatives, and a mental status examination, and yet we do …

In vivo assessment of neurotransmitters and modulators with magnetic resonance spectroscopy: application to schizophrenia

SA Wijtenburg, S Yang, BA Fischer… - … & Biobehavioral Reviews, 2015 - Elsevier
In vivo measurement of neurotransmitters and modulators is now feasible with advanced
proton magnetic resonance spectroscopy (1 H MRS) techniques. This review provides a …

Impact of peripheral levels of chemokines, BDNF and oxidative markers on cognition in individuals with schizophrenia

E Asevedo, A Gadelha, C Noto, RB Mansur… - Journal of psychiatric …, 2013 - Elsevier
Objective To investigate possible differences in peripheral levels of chemokines, BDNF and
oxidative markers between patients with Schizophrenia (SZ) and matched healthy controls …

Evaluation of malondialdehyde, superoxide dismutase and catalase activity and their diagnostic value in drug naïve, first episode, non-smoker major depression …

MA Camkurt, E Fındıklı, F İzci, EB Kurutaş, TC Tuman - Psychiatry research, 2016 - Elsevier
Major depression is a most frequent disorder, its diagnosis depends on patient interview,
and yet we do not have a reliable biomarker for depression. Oxidative stress is defined as …

NOX2 as a target for drug development: indications, possible complications, and progress

BA Diebold, SME Smith, Y Li… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: NOX2 is important for host defense, and yet is implicated in a large number of
diseases in which inflammation plays a role in pathogenesis. These include acute and …

Omega-3 prevents behavior response and brain oxidative damage in the ketamine model of schizophrenia

AI Zugno, HL Chipindo, AM Volpato, J Budni… - Neuroscience, 2014 - Elsevier
Supplementation with omega-3 has been identified as an adjunctive alternative for the
treatment of psychiatric disorders, in order to minimize symptoms. Considering the lack of …

A multimodal approach to studying the relationship between peripheral glutathione, brain glutamate, and cognition in health and in schizophrenia

JM Coughlin, K Yang, A Marsman, S Pradhan… - Molecular …, 2021 - nature.com
Involvement of oxidative stress in the pathophysiology of schizophrenia (SZ) is suggested by
studies of peripheral tissue. Nonetheless, it is unclear how such biological changes are …