Tissue deposition of protein fibrils causes a group of rare diseases called systemic
amyloidoses. This Seminar focuses on changes in their epidemiology, the current approach …

Alzheimer's disease (AD) is characterized by a chronic and progressive neurodegenerative
process resulting from the intracellular and extracellular accumulation of fibrillary proteins …

One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …

Amyloid fibers and oligomers are associated with a great variety of human diseases
including Alzheimer's disease and the prion conditions. Here we attempt to connect recent …

Transthyretin cardiac amyloidosis (ATTR‐CA) demonstrates progressive, potentially fatal,
and infiltrative cardiomyopathy caused by extracellular deposition of transthyretin‐derived …

This review is concerned with the role of fibrillization of the amyloid β (Aβ)-peptide in
Alzheimer's disease (AD). The perspective is that of a physical chemist, and one aim is to …

Background The amyloid fibril deposits that cause systemic amyloidosis always contain the
nonfibrillar normal plasma protein, serum amyloid P component (SAP). The drug (R)-1-[6 …

In the mid 1990s, immunoassays for C-reactive protein (CRP), with greater sensitivity than
those previously in routine use, revealed that increased CRP values, even within the range …

A growing number of diseases seem to be associated with inappropriate deposition of
protein aggregates. Some of these diseases—such as Alzheimer's disease and systemic …

Amyloidosis affects millions of people, as a cause of Alzheimer's disease or a complication
of dialysis, and also causes rare conditions. The many forms of the disorder have one …