The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …

Complex microbial communities shape the dynamics of various environments, ranging from
the mammalian gastrointestinal tract to the soil. Advances in DNA sequencing technologies …

The discovery of antibiotics more than 80 years ago has led to considerable improvements
in human and animal health. Although antibiotic resistance in environmental bacteria is …

In recent years, there has been an increasing interest in bacteriophages, which has led to
growing numbers of bacteriophage genomic sequences becoming available. Consequently …

Background Viruses are a significant player in many biosphere and human ecosystems, but
most signals remain “hidden” in metagenomic/metatranscriptomic sequence datasets due to …

Large serine recombinases (LSRs) are DNA integrases that facilitate the site-specific
integration of mobile genetic elements into bacterial genomes. Only a few LSRs, such as …

The antitumor efficacy of cancer immunotherapy can correlate with the presence of certain
bacterial species within the gut microbiome. However, many of the molecular mechanisms …

A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella
pneumoniae infection after long-term (> 700 days) antibiotic therapy is treated with a pre …

Bacteria have evolved diverse immunity mechanisms to protect themselves against the
constant onslaught of bacteriophages,–. Similar to how eukaryotic innate immune systems …

Background Viruses are central to microbial community structure in all environments. The
ability to generate large metagenomic assemblies of mixed microbial and viral sequences …