Thiazole-containing compounds as therapeutic targets for cancer therapy
In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …
development, and several new anticancer agents of natural and synthetic origin have been …
Development and therapeutic potential of 2-aminothiazole derivatives in anticancer drug discovery
SR Alizadeh, SM Hashemi - Medicinal Chemistry Research, 2021 - Springer
Currently, the development of anticancer drug resistance is significantly restricted the clinical
efficacy of the most commonly prescribed anticancer drug. Malignant disease is widely …
efficacy of the most commonly prescribed anticancer drug. Malignant disease is widely …
Synthesis and molecular docking of some novel 3-thiazolyl-coumarins as inhibitors of VEGFR-2 kinase
One crucial strategy for the treatment of breast cancer involves focusing on the Vascular
Endothelial Growth Factor Receptor (VEGFR-2) signaling system. Consequently, the …
Endothelial Growth Factor Receptor (VEGFR-2) signaling system. Consequently, the …
[HTML][HTML] Antiproliferative activity of thiazole and oxazole derivatives: A systematic review of in vitro and in vivo studies
NY Guerrero-Pepinosa, MC Cardona-Trujillo… - Biomedicine & …, 2021 - Elsevier
Thiazole and oxazole are compounds with a heterocyclic nucleus that have attracted the
attention of medicinal chemistry due to the great variety of biological activities that they …
attention of medicinal chemistry due to the great variety of biological activities that they …
Efficient synthesis, antibacterial, antifungal, antioxidant and cytotoxicity study of 2‐(2‐hydrazineyl) thiazole derivatives
VA Adole, RA More, BS Jagdale, TB Pawar… - …, 2020 - Wiley Online Library
In the present investigation, an alluring green PEG‐400 mediated one‐pot synthesis of
novel 2‐(2‐hydrazinyl) thiazole derivatives from 1, 2, 6, 7‐tetrahydro‐8H‐indeno [5, 4‐b] …
novel 2‐(2‐hydrazinyl) thiazole derivatives from 1, 2, 6, 7‐tetrahydro‐8H‐indeno [5, 4‐b] …
2-Aminothiazole: A privileged scaffold for the discovery of anti-cancer agents
Y Wan, J Long, H Gao, Z Tang - European Journal of Medicinal Chemistry, 2021 - Elsevier
Cancer has been the second heath killer being next only to cardiovascular diseases in
human society. Although many efforts have been taken for cancer therapy and many …
human society. Although many efforts have been taken for cancer therapy and many …
Synthesis, in vitro evaluation and molecular docking studies of novel thiophenyl thiazolyl-pyridine hybrids as potential anticancer agents
FO Ashmawy, SM Gomha, MA Abdallah, MEA Zaki… - Molecules, 2023 - mdpi.com
Many literature reports revealed the anticancer activity of pyridine and thiazole derivatives,
especially in lung cancer. Therefore, a new series of thiazolyl pyridines linked with …
especially in lung cancer. Therefore, a new series of thiazolyl pyridines linked with …
Thiazole–chalcone hybrids as prospective antitubercular and antiproliferative agents: Design, synthesis, biological, molecular docking studies and in silico ADME …
AB Kasetti, I Singhvi, R Nagasuri, RR Bhandare… - Molecules, 2021 - mdpi.com
Compounds bearing thiazole and chalcone pharmacophores have been reported to
possess excellent antitubercular and anticancer activities. In view of this, we designed …
possess excellent antitubercular and anticancer activities. In view of this, we designed …
Synthesis, molecular docking and antiproliferative activity studies of a thiazole‐based compound linked to hydrazone moiety
Abstract (A new 4‐oxothiazolidin‐2‐ylidene derivative bearing hydrazone moiety was
synthesized via Michael addition between the reaction of 4‐(4‐nitrophenyl)‐3 …
synthesized via Michael addition between the reaction of 4‐(4‐nitrophenyl)‐3 …
Thiazole, thio and semicarbazone derivatives against tropical infective diseases: Chagas disease, human African trypanosomiasis (HAT), leishmaniasis, and malaria
CB Scarim, DH Jornada, MGM Machado… - European journal of …, 2019 - Elsevier
Thiazole, thiosemicarbazone and semicarbazone moieties are privileged scaffolds (acting
as primary pharmacophores) in many compounds that are useful to treat several diseases …
as primary pharmacophores) in many compounds that are useful to treat several diseases …