Recent trends of self-emulsifying drug delivery system for enhancing the oral bioavailability of poorly water-soluble drugs

P Tran, JS Park - Journal of Pharmaceutical Investigation, 2021 - Springer
Background The oral route is the most popular route for the clinical administration of drugs to
treat various diseases. Before a drug is absorbed into the blood circulation, it must undergo …

Design, development, and evaluation of spray dried flurbiprofen loaded sustained release polymeric nanoparticles using QBD approach to manage inflammation

S Mandpe, E Kole, V Parate, A Chatterjee… - Drying …, 2023 - Taylor & Francis
Spray-dried Flurbiprofen (FLB) loaded polymeric nanoformulation using Eudragit L 100 and
Ethylcellulose. They were optimized and evaluated. This study determined drug release (%) …

Quality by design enabled development of oral self-nanoemulsifying drug delivery system of a novel calcimimetic cinacalcet HCl using a porous carrier: in vitro and in …

KC Panigrahi, CN Patra, MEB Rao - AAPS PharmSciTech, 2019 - Springer
In this present research, work quality by design-enabled development of cinacalcet HCl
(CH)-loaded solid self-nanoemulsifying drug delivery system (S-SNEDDS) was conducted …

Drug loading of tannic acid crosslinked hydroxyapatite/gelatin composites via spray dryer and kinetic studies

IB Gumus, E Kahraman, N Erdol-Aydin… - Drying …, 2023 - Taylor & Francis
The present study aims at studying the loading and release of 5-Fluorouracil (5-FU) drug
from hydroxyapatite/gelatin (HAp-GEL) composites. Composites were produced in the …

Formulation and evaluation of solid self-microemulsifying drug delivery system of chlorthalidone by spray drying technology

JK Madagul, DR Parakh, RS Kumar… - Drying …, 2017 - Taylor & Francis
The main objective of this study was to prepare a solid self-microemulsifying drug delivery
system (S-SMEDDS) by spray drying liquid SMEDDS with an inert solid carrier Aerosil 200 …

Development of self-microemulsifying drug delivery system of mebendazole by spray drying technology: characterization, in vitro and in vivo evaluation

DR Parakh, MP Patil, NL Dashputre… - Drying …, 2016 - Taylor & Francis
In this study, a novel liquid self-microemulsifying drug delivery system (SMEDDS) containing
mebendazole was formulated and further developed into a solid form by a spray drying …

Application of factorial design approach in development and evaluation of self microemulsifying drug delivery system (SMEDDS) of mebendazole

DR Parakh, MP Patil, SS Sonawane… - Journal of …, 2017 - Springer
Self microemulsifying drug delivery systems (SMEDDS) are defined as isotropic mixtures of
natural or synthetic oils, surfactants and co-solvents/co-surfactants. Upon mild agitation …

[HTML][HTML] Development and Evaluation of a Solid Self-Microemulsifying Drug Delivery System Containing Cilostazol Using the Spray Drying Technique

M Patil, A Yadav, R Mogal, M Shaikh… - Biosciences …, 2024 - biotech-asia.org
A robust self-emulsifying formulation containing cilostazol was produced by mixing
hydrophilic surfactants with oil. Considering cilostazol's limited solubility and bioavailability …

Solid self nano-emulsifying system for the enhancement of dissolution and bioavailability of Prasugrel HCl: in vitro and in vivo studies

M Khanfar, S Al-Nimry, S Attar - Pharmaceutical Development and …, 2021 - Taylor & Francis
Abstract Prasugrel Hydrochloride (PHCl) is an antiplatelet drug. It is a class II drug with
variable bioavailability. The objective of this work was to enhance the solubility and hence …

Impact on HDL and LDL of Hyperlipidemic Rat Models: Designed Solid Self-Nanoemulsifying Drug Delivery Systems with Atorvastatin and Ezetimibe combination

AR Gardouh, AM Nasef, Y Mostafa… - Research Journal of …, 2022 - indianjournals.com
The main purpose of this study was to develop and evaluate solid self-nanoemulsifying drug
delivery systems (S-SNEDDs) of Atorvastatin/Ezetimibe combination to combine the …