Psychostimulants and cognition: a continuum of behavioral and cognitive activation

S Wood, JR Sage, T Shuman, SG Anagnostaras - Pharmacological reviews, 2014 - ASPET
Psychostimulants such as cocaine have been used as performance enhancers throughout
recorded history. Although psychostimulants are commonly prescribed to improve attention …

MDMA and memory, addiction, and depression: dose-effect analysis

MM Pantoni, JL Kim, KR Van Alstyne… - …, 2022 - Springer
Abstract Rationale±3, 4-Methylenedioxymethamphetamine (MDMA) is a recreational drug
that shows substantial promise as a psychotherapeutic agent. Still, there is some concern …

Automated assessment of pavlovian conditioned freezing and shock reactivity in mice using the video freeze system

SG Anagnostaras, SC Wood, T Shuman… - Frontiers in behavioral …, 2010 - frontiersin.org
The Pavlovian conditioned freezing paradigm has become a prominent mouse and rat
model of learning and memory, as well as of pathological fear. Due to its efficiency …

Nano-zinc oxide damages spatial cognition capability via over-enhanced long-term potentiation in hippocampus of Wistar rats

D Han, Y Tian, T Zhang, G Ren… - International journal of …, 2011 - Taylor & Francis
This study focused on the effects of zinc oxide nanoparticles (nano-ZnO) on spatial learning
and memory and synaptic plasticity in the hippocampus of young rats, and tried to interpret …

FoxO6 regulates memory consolidation and synaptic function

DAM Salih, AJ Rashid, D Colas… - Genes & …, 2012 - genesdev.cshlp.org
The FoxO family of transcription factors is known to slow aging downstream from the
insulin/IGF (insulin-like growth factor) signaling pathway. The most recently discovered FoxO …

Enhanced neuroinflammation mediated by DNA methylation of the glucocorticoid receptor triggers cognitive dysfunction after sevoflurane anesthesia in adult rats …

Y Zhu, Y Wang, R Yao, T Hao, J Cao, H Huang… - Journal of …, 2017 - Springer
Background Mounting evidence indicates that children who experience abuse and neglect
are prone to chronic diseases and premature mortality later in life. One mechanistic …

The likelihood of cognitive enhancement

G Lynch, LC Palmer, CM Gall - Pharmacology Biochemistry and Behavior, 2011 - Elsevier
Whether drugs that enhance cognition in healthy individuals will appear in the near future
has become a topic of considerable interest. We address this possibility using a three …

The efficacy of modafinil as a cognitive enhancer: a systematic review and meta-analysis

MA Kredlow, A Keshishian… - Journal of clinical …, 2019 - journals.lww.com
Background Animal models and human studies have identified the potential of modafinil as
a cognitive enhancing agent, independent of its effects on promoting wakefulness in sleep …

Psychostimulant use disorder, an unmet therapeutic goal: can modafinil narrow the gap?

M Hersey, AK Bacon, LG Bailey… - Frontiers in …, 2021 - frontiersin.org
The number of individuals affected by psychostimulant use disorder (PSUD) has increased
rapidly over the last few decades resulting in economic, emotional, and physical burdens on …

Sleep selectively enhances hippocampus-dependent memory in mice.

DJ Cai, T Shuman, MR Gorman, JR Sage… - Behavioral …, 2009 - psycnet.apa.org
Sleep has been implicated as playing a critical role in memory consolidation. Emerging
evidence suggests that reactivation of memories during sleep may facilitate the transfer of …