The diversification of methods for studying cell–cell interactions and communication
No cell lives in a vacuum, and the molecular interactions between cells define most
phenotypes. Transcriptomics provides rich information to infer cell–cell interactions and …
phenotypes. Transcriptomics provides rich information to infer cell–cell interactions and …
Computational cell–cell interaction technologies drive mechanistic and biomarker discovery in the tumor microenvironment
Highlights•Tumor-immune CCIs can be investigated using scRNA-seq and ST
strategies.•CCI studies elucidate fundamental mechanisms in disease state.•Open-source …
strategies.•CCI studies elucidate fundamental mechanisms in disease state.•Open-source …
LIANA+ provides an all-in-one framework for cell–cell communication inference
The growing availability of single-cell and spatially resolved transcriptomics has led to the
development of many approaches to infer cell–cell communication, each capturing only a …
development of many approaches to infer cell–cell communication, each capturing only a …
Multicellular factor analysis of single-cell data for a tissue-centric understanding of disease
Biomedical single-cell atlases describe disease at the cellular level. However, analysis of
this data commonly focuses on cell-type-centric pairwise cross-condition comparisons …
this data commonly focuses on cell-type-centric pairwise cross-condition comparisons …
LIANA+: an all-in-one cell-cell communication framework
The growing availability of single-cell and spatially-resolved transcriptomics has led to the
rapidly growing popularity of methods to infer cell-cell communication. Many approaches …
rapidly growing popularity of methods to infer cell-cell communication. Many approaches …
Sctensor detects many-to-many cell–cell interactions from single cell RNA-sequencing data
K Tsuyuzaki, M Ishii, I Nikaido - BMC bioinformatics, 2023 - Springer
Background Complex biological systems are described as a multitude of cell–cell
interactions (CCIs). Recent single-cell RNA-sequencing studies focus on CCIs based on …
interactions (CCIs). Recent single-cell RNA-sequencing studies focus on CCIs based on …
Modelling Cell-cell Communication using Prior Knowledge with Single-cell and Spatially-resolved Omics Data
D Dimitrov - 2024 - archiv.ub.uni-heidelberg.de
Cell-cell communication (CCC) is a dynamic process which governs and coordinates
diverse biological functions. The popularity of single-cell and spatially-resolved …
diverse biological functions. The popularity of single-cell and spatially-resolved …
[引用][C] Modelling Cell-cell Communication using Prior Knowledge with Single-cell and Spatially-resolved Omics Data
J Saez-Rodriguez