The diversification of methods for studying cell–cell interactions and communication

E Armingol, HM Baghdassarian, NE Lewis - Nature Reviews Genetics, 2024 - nature.com
No cell lives in a vacuum, and the molecular interactions between cells define most
phenotypes. Transcriptomics provides rich information to infer cell–cell interactions and …

Computational cell–cell interaction technologies drive mechanistic and biomarker discovery in the tumor microenvironment

A Pong, CK Mah, GW Yeo, NE Lewis - Current Opinion in Biotechnology, 2024 - Elsevier
Highlights•Tumor-immune CCIs can be investigated using scRNA-seq and ST
strategies.•CCI studies elucidate fundamental mechanisms in disease state.•Open-source …

LIANA+ provides an all-in-one framework for cell–cell communication inference

D Dimitrov, PSL Schäfer, E Farr, P Rodriguez-Mier… - Nature Cell …, 2024 - nature.com
The growing availability of single-cell and spatially resolved transcriptomics has led to the
development of many approaches to infer cell–cell communication, each capturing only a …

Multicellular factor analysis of single-cell data for a tissue-centric understanding of disease

ROR Flores, JD Lanzer, D Dimitrov, B Velten… - Elife, 2023 - elifesciences.org
Biomedical single-cell atlases describe disease at the cellular level. However, analysis of
this data commonly focuses on cell-type-centric pairwise cross-condition comparisons …

LIANA+: an all-in-one cell-cell communication framework

D Dimitrov, PSL Schäfer, E Farr, P Rodriguez Mier… - BioRxiv, 2023 - biorxiv.org
The growing availability of single-cell and spatially-resolved transcriptomics has led to the
rapidly growing popularity of methods to infer cell-cell communication. Many approaches …

Sctensor detects many-to-many cell–cell interactions from single cell RNA-sequencing data

K Tsuyuzaki, M Ishii, I Nikaido - BMC bioinformatics, 2023 - Springer
Background Complex biological systems are described as a multitude of cell–cell
interactions (CCIs). Recent single-cell RNA-sequencing studies focus on CCIs based on …

Modelling Cell-cell Communication using Prior Knowledge with Single-cell and Spatially-resolved Omics Data

D Dimitrov - 2024 - archiv.ub.uni-heidelberg.de
Cell-cell communication (CCC) is a dynamic process which governs and coordinates
diverse biological functions. The popularity of single-cell and spatially-resolved …

[引用][C] Modelling Cell-cell Communication using Prior Knowledge with Single-cell and Spatially-resolved Omics Data

J Saez-Rodriguez