From viruses to cancer: exploring the role of the hepatitis C virus NS3 protein in carcinogenesis

CA Martineau, N Rivard, M Bisaillon - Infectious Agents and Cancer, 2024 - Springer
Hepatitis C virus (HCV) chronically infects approximately 170 million people worldwide and
is a known etiological agent of hepatocellular carcinoma (HCC). The molecular mechanisms …

Development of a pseudo-typed virus particle based method to determine the efficacy of virucidal agents

J Thomas, F Mughal, KJ Roper, A Kotsiri, W Albalawi… - Scientific Reports, 2024 - nature.com
Abstract The ongoing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
pandemic has highlighted the threat that viral outbreaks pose to global health. A key tool in …

Studying Host-Virus Interactions with Pseudotyped Viruses (Video)| JoVE

T Fantoni, M Bissoli, C Stefani, M Voi, A Dabija… - JoVE (Journal of …, 2023 - jove.com
Pseudotyped viruses (PVs) are molecular tools that can be used to study host-virus
interactions and to test the neutralizing ability of serum samples, in addition to their better …

SARS-CoV-2 S, M and E Structural Proteins Down-modulate HIV-1 LTR Activity and Modulate Endoplasmic Reticulum Stress Responses

W Albalawi, J Thomas, F Mughal, KJ Roper, A Alshehri… - bioRxiv, 2024 - biorxiv.org
We have previously shown that the Hepatitis C Virus (HCV) E1E2 envelope glycoprotein can
down-modulate HIV-1 long-terminal repeat (LTR) activity through disruption to NF-kappaB …

The use of SARS-CoV-2 pseudoviruses to investigate the neutralizing immunity and the pathogenesis of COVID-19

T Fantoni - 2024 - iris.univr.it
Abstract The Coronavirus Disease–19 (COVID-19) occurs following SARS-CoV-2 infection
with a wide spectrum of symptoms, which degenerate into severe acute respiratory …