Role of cAMP modulator supplementations during oocyte in vitro maturation in domestic animals
GR Leal, CAS Monteiro, JMG Souza-Fabjan… - Animal reproduction …, 2018 - Elsevier
Cyclic adenosine monophosphate (cAMP) is an important molecule in signal transduction
within the cell, functioning as a second cell messenger of gonadotrophin stimulation. The …
within the cell, functioning as a second cell messenger of gonadotrophin stimulation. The …
The Simulated Physiological Oocyte Maturation (SPOM) system in domestic animals: A systematic review
GR Leal, CAS Monteiro, L de Rezende Carvalheira… - Theriogenology, 2022 - Elsevier
Abstract Simulated Physiological Oocyte Maturation (SPOM) mimics in vitro the
physiological events of oocyte maturation. The system uses cAMP modulators in two steps …
physiological events of oocyte maturation. The system uses cAMP modulators in two steps …
Conditions to optimise the developmental competence of immature equine oocytes
ES Metcalf, KR Masterson, D Battaglia… - Reproduction …, 2020 - CSIRO Publishing
Optimising the developmental potential of immature equine oocytes and in vitro-produced
(IVP) embryos was explored through modifications of established media and holding …
(IVP) embryos was explored through modifications of established media and holding …
The role of forskolin as a lipolytic stimulator during in vitro oocyte maturation and the in vitro embryo production of livestock
SHA Raza, AH Abd El‐Aziz… - … in Domestic Animals, 2021 - Wiley Online Library
Cryopreservation is a modern technique which assists in the preservation of genetic material
from oocytes and embryos for a long time. However, elevated vulnerability to …
from oocytes and embryos for a long time. However, elevated vulnerability to …
Lipid modulation during IVM increases the metabolism and improves the cryosurvival of cat oocytes
GR Leal, T de Almeida Oliveira… - Theriogenology, 2024 - Elsevier
This study investigated the time course of lipid accumulation during IVM and assessed the
role of lipid modulators added during IVM on lipid content, nuclear maturation, oxidative …
role of lipid modulators added during IVM on lipid content, nuclear maturation, oxidative …
The SPOM-adapted IVM system improves in vitro production of bovine embryos
GR Leal, MAG Graciosa, CAS Monteiro, R Pasolini… - Theriogenology, 2020 - Elsevier
This study aimed to test the effects of an IVM SPOM adaptation (SPOM-adapted IVM) on the
production, total number of cells (TNC), apoptosis, and cryotolerance (post-warming survival …
production, total number of cells (TNC), apoptosis, and cryotolerance (post-warming survival …
Combined use of dbcAMP and IBMX minimizes the damage induced by a long‐term artificial meiotic arrest in mouse germinal vesicle oocytes
XC Wu, Z Han, X Hao, YT Zhao, CJ Zhou… - Molecular …, 2020 - Wiley Online Library
Phosphodiesterase (PDE)‐mediated reduction of cyclic adenosine monophosphate (cAMP)
activity can initiate germinal vesicle (GV) breakdown in mammalian oocytes. It is crucial to …
activity can initiate germinal vesicle (GV) breakdown in mammalian oocytes. It is crucial to …