Automated chemical oligosaccharide synthesis: novel approach to traditional challenges
Advances in carbohydrate chemistry have certainly made common oligosaccharides much
more accessible. However, many current methods still rely heavily upon specialized …
more accessible. However, many current methods still rely heavily upon specialized …
“One-pot” protection, glycosylation, and protection–glycosylation strategies of carbohydrates
SS Kulkarni, CC Wang, NM Sabbavarapu… - Chemical …, 2018 - ACS Publications
Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play
significant roles in a variety of vital biological processes. Access to unique and …
significant roles in a variety of vital biological processes. Access to unique and …
[HTML][HTML] Stereocontrolled 1, 2-cis glycosylation as the driving force of progress in synthetic carbohydrate chemistry
SS Nigudkar, AV Demchenko - Chemical science, 2015 - pubs.rsc.org
Recent developments in stereoselective 1, 2-cis glycosylation that have emerged during the
past decade are surveyed herein. For detailed coverage of the previous achievements in the …
past decade are surveyed herein. For detailed coverage of the previous achievements in the …
Oligosaccharide synthesis and translational innovation
L Krasnova, CH Wong - Journal of the American Chemical Society, 2019 - ACS Publications
The translation of biological glycosylation in humans to the clinical applications involves
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …
New principles for glycoside‐bond formation
X Zhu, RR Schmidt - Angewandte Chemie International Edition, 2009 - Wiley Online Library
Meeting the demand for sugars: The importance of oligosaccharides and glycoconjugates in
biological systems has stimulated a need to access significant amounts of these …
biological systems has stimulated a need to access significant amounts of these …
[HTML][HTML] Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research
TJ Boltje, T Buskas, GJ Boons - Nature chemistry, 2009 - nature.com
Synthetic oligosaccharides and glycoconjugates are increasingly used as probes for
biological research and as lead compounds for drug and vaccine discovery. These …
biological research and as lead compounds for drug and vaccine discovery. These …
Chemical O‐Glycosylations: An Overview
R Das, B Mukhopadhyay - ChemistryOpen, 2016 - Wiley Online Library
The development of glycobiology relies on the sources of particular oligosaccharides in their
purest forms. As the isolation of the oligosaccharide structures from natural sources is not a …
purest forms. As the isolation of the oligosaccharide structures from natural sources is not a …
Mechanisms of glycosylation reactions studied by low-temperature nuclear magnetic resonance
TG Frihed, M Bols, CM Pedersen - Chemical reviews, 2015 - ACS Publications
Synthesis of oligosaccharides has, for the past couple of decades, been greatly improved by
new methods and the ongoing development of new technologies, such as automation in …
new methods and the ongoing development of new technologies, such as automation in …
[HTML][HTML] Protecting groups in carbohydrate chemistry: influence on stereoselectivity of glycosylations
J Guo, XS Ye - Molecules, 2010 - mdpi.com
Saccharides are polyhydroxy compounds, and their synthesis requires complex protecting
group manipulations. Protecting groups are usually used to temporarily mask a functional …
group manipulations. Protecting groups are usually used to temporarily mask a functional …
Boronic-Acid-Catalyzed Regioselective and 1,2-cis-Stereoselective Glycosylation of Unprotected Sugar Acceptors via SNi-Type Mechanism
M Tanaka, A Nakagawa, N Nishi, K Iijima… - Journal of the …, 2018 - ACS Publications
Regio-and 1, 2-cis-stereoselective chemical glycosylation of unprotected glycosyl acceptors
has been in great demand for the efficient synthesis of natural glycosides. However …
has been in great demand for the efficient synthesis of natural glycosides. However …