Association between methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms and essential hypertension: a systematic review and meta …

YL Wu, CY Hu, SS Lu, FF Gong, F Feng, ZZ Qian… - Metabolism, 2014 - Elsevier
Objective Many studies have investigated the role of 5, 10-methylenetetrahydrofolate
reductase gene (MTHFR) C677T/A1298C polymorphisms in essential hypertension (EH) …

Matrix metalloproteinases and genetic mouse models in cancer research: a mini-review

E Wieczorek, E Jablonska, W Wasowicz, E Reszka - Tumor Biology, 2015 - Springer
Carcinogenesis is a multistep and also a multifactorial process that involves agents like
genetic and environmental factors. Matrix metalloproteinases (MMPs) are major proteolytic …

[HTML][HTML] Homocysteine levels, H-Hypertension, and the MTHFR C677T genotypes: A complex interaction

C Al Hageh, E Alefishat, M Ghassibe-Sabbagh… - Heliyon, 2023 - cell.com
Background and objectives High homocysteine levels are associated with increased risk of
hypertension and stroke. Homocysteine is metabolized by the methylenetetrahydrofolate …

Type II diabetes mellitus and hyperhomocysteinemia: a complex interaction

DE Platt, E Hariri, P Salameh, M Merhi… - Diabetology & metabolic …, 2017 - Springer
Abstract Background Elevated homocysteine (Hc) levels have a well-established and clear
causal relationship to epithelial damage leading to coronary artery disease. Furthermore, it …

APOE gene ɛ4 allele (388C‐526C) effects on serum lipids and risk of coronary artery disease in southern Chinese Hakka population

Q Liu, H Wu, Z Yu, Q Huang… - Journal of Clinical …, 2021 - Wiley Online Library
Objective To analyze the relationship of Apolipoprotein E (APOE) and solute carrier organic
anion transporter family member 1B1 (SLCO1B1) gene polymorphisms with coronary artery …

Oxidative stress in coronary artery disease: epigenetic perspective

SVV Lakshmi, SM Naushad, CA Reddy… - Molecular and cellular …, 2013 - Springer
The association between oxidative stress and coronary artery disease (CAD) is well
documented. However, the role of epigenetic factors contributing to oxidative stress is …

Relationship between homocysteine and chronic total coronary occlusion: a cross-sectional study from southwest China

K Xiao, Z Xv, L Liu, B Yang, H Cao, J Wang… - Cardiology in the …, 2024 - cambridge.org
Background: Chronic total coronary occlusion is among the most complex coronary artery
diseases. Elevated homocysteine is a risk factor for coronary artery diseases. However, few …

Analysis of differentially expressed genes in coronary artery disease by integrated microarray analysis

MV Balashanmugam, TB Shivanandappa… - Biomolecules, 2019 - mdpi.com
Coronary artery disease (CAD) is a major cause of end-stage cardiac disease. Although
profound efforts have been made to illuminate the pathogenesis, the molecular mechanisms …

Fulvic acid attenuates homocysteine-induced cyclooxygenase-2 expression in human monocytes

SJ Chien, TC Chen, HC Kuo, CN Chen… - … and Alternative Medicine, 2015 - Springer
Background Homocysteine and pro-inflammatory mediators such as cyclooxygenase-2
(COX-2) have been linked to vascular dysfunction and risks of cardiovascular diseases …

[引用][C] 冠状动脉狭窄程度与冠心病危险因素的相关性分析

祝小霞, 丁旵东, 曾胜煌, 郝睿 - 中华老年心脑血管病杂志, 2014