[HTML][HTML] Hand, foot and mouth disease (HFMD): emerging epidemiology and the need for a vaccine strategy

S Aswathyraj, G Arunkumar, EK Alidjinou… - Medical microbiology and …, 2016 - Springer
Hand, foot, and mouth disease (HFMD) is a contagious viral disease and mainly affects
infants and young children. The main manifestations are fever, vesicular rashes on hand …

EV71 vaccine, a new tool to control outbreaks of hand, foot and mouth disease (HFMD)

Q Mao, Y Wang, L Bian, M Xu, Z Liang - Expert review of vaccines, 2016 - Taylor & Francis
ABSTRACT On December 3rd 2015, the China Food and Drug Administration (CFDA)
approved the first inactivated Enterovirus 71 (EV71) whole virus vaccine for preventing …

Annexin II binds to capsid protein VP1 of enterovirus 71 and enhances viral infectivity

SL Yang, YT Chou, CN Wu, MS Ho - Journal of virology, 2011 - Am Soc Microbiol
ABSTRACT Enterovirus type 71 (EV71) causes hand, foot, and mouth disease (HFMD),
which is mostly self-limited but may be complicated with a severe to fatal neurological …

Immunization with virus-like particles of enterovirus 71 elicits potent immune responses and protects mice against lethal challenge

YC Chung, MS Ho, JC Wu, WJ Chen, JH Huang… - Vaccine, 2008 - Elsevier
Enterovirus 71 (EV71) is an etiologic agent responsible for seasonal epidemics of hand-foot-
and-mouth disease and causes outbreaks with significant mortality among young children …

Molecular epidemiology of enterovirus 71 infection in the Western Pacific Region

H Shimizu, A Utama, N Onnimala, C Li… - Pediatrics …, 2004 - Wiley Online Library
Background: Recently, there have been large outbreaks of hand, foot and mouth disease
(HFMD) mainly caused by enterovirus 71 (EV71) associated with severe neurological …

EV71: an emerging infectious disease vaccine target in the Far East?

J Xu, Y Qian, S Wang, JMG Serrano, W Li, Z Huang… - Vaccine, 2010 - Elsevier
Hand, foot, and mouth disease (HFMD) is a common viral illness in infants and children
caused by viruses that belong to the enterovirus genus of the picornavirus family. Although …

[HTML][HTML] Purification and characterization of enterovirus 71 viral particles produced from vero cells grown in a serum-free microcarrier bioreactor system

CC Liu, MS Guo, FHY Lin, KN Hsiao, KHW Chang… - PloS one, 2011 - journals.plos.org
Background Enterovirus 71 (EV71) infections manifest most commonly as a childhood
exanthema known as hand-foot-and-mouth disease (HFMD) and can cause neurological …

The virology and developments toward control of human enterovirus 71

L Yi, J Lu, H Kung, ML He - Critical reviews in microbiology, 2011 - Taylor & Francis
Enterovirus 71 (EV71), a member of the Enterovirus genus in the Picornaviridae family, was
first recognized as a dermotrophic virus that usually cause mild, self-limiting hand-foot-and …

Epidemiological and etiological characteristics of hand, foot, and mouth disease in Wuhan, China from 2012 to 2013: outbreaks of coxsackieviruses A10

Q Yang, J Ding, J Cao, Q Huang… - Journal of medical …, 2015 - Wiley Online Library
Hand‐foot‐mouth disease (HFMD) is a common infectious disease which often occurs in
young children. It is caused by enteroviruses, most commonly enterovirus71 (EV71) and …

Enterovirus 71 infection of human dendritic cells

YW Lin, SW Wang, YY Tung… - … biology and medicine, 2009 - journals.sagepub.com
Enterovirus 71 (EV71) causes death and long-term neurologic sequelae in hundreds of
thousands of young children, but its pathogenesis remains elusive. Dendritic cells (DCs) …