Oxidative stress is important in the pathophysiology of obesity, altering regulatory factors of
mitochondrial activity, modifying the concentration of inflammation mediators associated with …

Diabesity is a term used to describe the combined adverse health effects of obesity and
diabetes mellitus. The worldwide dual epidemic of obesity and type 2 diabetes is an …

Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Chronic jet lag induces spontaneous hepatocellular carcinoma (HCC) in wild-type mice
following a mechanism very similar to that observed in obese humans. The process initiates …

Abstract The “metabolic syndrome”(MetS) is a clustering of components that reflect
overnutrition, sedentary lifestyles, and resultant excess adiposity. The MetS includes the …

Obesity, particularly severe obesity is capable of producing hemodynamic alterations that
contribute to changes in cardiac morphology which may predispose to impairment of …

Green tea catechins (GTC) are polyphenolic compounds present in the unfermented dried
leaves of the plant, Camellia sinensis. Results from a number of randomized, controlled …

A cornerstone for research into the link between stress and health has been the reactivity
hypothesis; cardiovascular reactivity to psychological stressors, if prolonged or exaggerated …

The transcriptional regulators Ebf2 and Prdm16 establish and maintain the brown and/or
beige fat cell identity. However, the mechanisms operating in white adipocytes to suppress …

The consequences of obstructive sleep apnea (OSA) are largely mediated by chronic
intermittent hypoxia and sleep fragmentation. The primary molecular domains affected are …