Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Epitope prediction by novel immunoinformatics approach: a state-of-the-art review

E Raoufi, M Hemmati, S Eftekhari, K Khaksaran… - International Journal of …, 2020 - Springer
Immunoinformatics is a science that helps to create significant immunological information
using bioinformatics softwares and applications. One of the most important applications of …

In-silico design of a multi-epitope vaccine candidate against onchocerciasis and related filarial diseases

RA Shey, SM Ghogomu, KK Esoh, ND Nebangwa… - Scientific reports, 2019 - nature.com
Onchocerciasis is a parasitic disease with high socio-economic burden particularly in sub-
Saharan Africa. The elimination plan for this disease has faced numerous challenges. A …

Designing a novel multi-epitope vaccine to evoke a robust immune response against pathogenic multidrug-resistant Enterococcus faecium bacterium

J Dey, SR Mahapatra, TK Raj, T Kaur, P Jain, A Tiwari… - Gut Pathogens, 2022 - Springer
Enterococcus faecium is an emerging ESKAPE bacterium that is capable of causing severe
public health complications in humans. There are currently no licensed treatments or …

Designing of a next generation multiepitope based vaccine (MEV) against SARS-COV-2: Immunoinformatics and in silico approaches

M Tahir ul Qamar, A Rehman, K Tusleem, UA Ashfaq… - PloS one, 2020 - journals.plos.org
Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
coronavirus 2 (SARS-COV-2) is a significant threat to global health security. Till date, no …

[HTML][HTML] Multi-epitope chimeric vaccine design against emerging Monkeypox virus via reverse vaccinology techniques- a bioinformatics and immunoinformatics …

S Aiman, Y Alhamhoom, F Ali, N Rahman… - Frontiers in …, 2022 - frontiersin.org
The emerging monkeypox virus (MPXV) is a zoonotic orthopoxvirus that causes infections in
humans similar to smallpox. Since May 2022, cases of monkeypox (MPX) have been …

Development of a multi-epitope peptide vaccine inducing robust T cell responses against brucellosis using immunoinformatics based approaches

M Saadi, A Karkhah, HR Nouri - Infection, Genetics and Evolution, 2017 - Elsevier
Current investigations have demonstrated that a multi-epitope peptide vaccine targeting
multiple antigens could be considered as an ideal approach for prevention and treatment of …

Design of a multi-epitope vaccine against SARS-CoV-2 using immunoinformatics approach

S Sanami, M Zandi, B Pourhossein, GR Mobini… - International journal of …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused COVID-19 disease
in China. So far, no vaccine has licensed to protect against infection with COVID-19 …

Design of a multi-epitope-based vaccine targeting M-protein of SARS-CoV2: an immunoinformatics approach

VS Ayyagari, V TC, AP K, K Srirama - Journal of biomolecular …, 2022 - Taylor & Francis
In the present study, one of the targets present on the envelopes of coronaviruses,
membrane glycoprotein (M) was chosen for the design of a multi-epitope vaccine by …

Immunoinformatics analysis and in silico designing of a novel multi-epitope peptide vaccine against Staphylococcus aureus

N Hajighahramani, N Nezafat, M Eslami… - Infection, Genetics and …, 2017 - Elsevier
Staphylococcus aureus is a pathogen that causes a variety of infections in humans.
Methicillin-resistant S. aureus, which is an antibiotic-resistant form, is responsible for …