Revisiting the roles of filaggrin in atopic dermatitis

V Moosbrugger-Martinz, C Leprince… - International Journal of …, 2022 - mdpi.com
The discovery in 2006 that loss-of-function mutations in the filaggrin gene (FLG) cause
ichthyosis vulgaris and can predispose to atopic dermatitis (AD) galvanized the dermatology …

American Academy of Dermatology Guidelines: awareness of comorbidities associated with atopic dermatitis in adults

DMR Davis, AM Drucker, A Alikhan, L Bercovitch… - Journal of the American …, 2022 - Elsevier
Background Studies found associations between atopic dermatitis (AD) and various
comorbidities. Objective To appraise evidence of the association between AD and …

Food allergy and asthma: is there a link?

JAM Emons, R Gerth van Wijk - Current treatment options in allergy, 2018 - Springer
Purpose of review To describe and understand the links and interactions between food
allergy and asthma Recent findings Food allergy and asthma are characterized by an …

Cohort profile: the Isle of Wight whole population birth cohort (IOWBC)

SH Arshad, JW Holloway, W Karmaus… - International journal …, 2018 - academic.oup.com
By the late 1980s, it was clear that allergic diseases, including asthma, eczema, allergic
rhinitis and food allergy, had been increasing in recent decades, but the extent of this …

Prevalence and early‐life risk factors of school‐age allergic multimorbidity: the EuroPrevall‐iFAAM birth cohort

ST Sigurdardottir, K Jonasson, M Clausen… - Allergy, 2021 - Wiley Online Library
Background Coexistence of childhood asthma, eczema and allergic rhinitis is higher than
can be expected by chance, suggesting a common mechanism. Data on allergic …

IgE antibodies in relation to prevalence and multimorbidity of eczema, asthma, and rhinitis from birth to adolescence

N Ballardini, A Bergström, CF Wahlgren, M Van Hage… - Allergy, 2016 - Wiley Online Library
Background Eczema, asthma, and rhinitis affect a large proportion of children, but their
prevalence varies with age. IgE antibodies are also common in the pediatric population …

Interrelationships between atopic disorders in children: a meta-analysis based on ISAAC questionnaires

DHJ Pols, JB Wartna, EI van Alphen, H Moed… - PLoS …, 2015 - journals.plos.org
Purpose To study the prevalence and interrelationship between asthma, allergic rhinitis and
eczema using data obtained from ISAAC questionnaires. Method The Medline, Pubmed …

[HTML][HTML] The majority of children sensitized before school-age develop allergic disease before adulthood: a longitudinal population-based study

J Bunne, L Hedman, M Perzanowski, A Bjerg… - The Journal of Allergy …, 2022 - Elsevier
Background Allergic sensitization increases the risk of asthma and allergic rhinitis, but the
impact of age at onset of sensitization is less studied. Objective To examine the cumulative …

Comorbidity of asthma and hypertension may be mediated by shared genetic dysregulation and drug side effects

O Zolotareva, OV Saik, C Königs, EY Bragina… - Scientific reports, 2019 - nature.com
Asthma and hypertension are complex diseases coinciding more frequently than expected
by chance. Unraveling the mechanisms of comorbidity of asthma and hypertension is …

Early-life gut microbiota associates with allergic rhinitis during 13-year follow-up in a Finnish probiotic intervention cohort

S Kallio, C Jian, K Korpela, AK Kukkonen… - Microbiology …, 2024 - Am Soc Microbiol
Perinatal and early-life factors reported to affect risk of allergic diseases may be mediated by
changes in the gut microbiota. Here, we explored the associations between the infant gut …